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Antidepressants & Weight Gain

How to Get Help without Gaining Weight


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I don’t have unipolar but I’ve been on some gainers’s been a matter usually of more hungry & most recently I was barely eating & it was just me getting my appetite back. I’ve since lost a lot of the weight. Thankfully my mood stabilizer is not a gainer, at least for me, but lamictal does seem to be pretty weight neutral. I notice my appetite is normal on it & I’m pretty up there dosage wise. I am on a low dose antidepressant (not an SSRI....those mess with me & informed my bipolar diagnosis back in ‘05) & seemingly no effect in that sense, I’m sleeping great though which is actually why I take it. Report
Add Diabetes into the mix, and life becomes even more complicated. It's not easy to be constantly vigilant, but vigilant we must be. Good luck to us all. 8-) Report
I've been clinically depressed for years and have been on many different medications as well as seeing a psychiatrist and going through a course of behavioural modification, which was very effective. I will be on antidepressants for the rest of my life, and have found one which is very effective for me. If it means carrying around a bit of extra weight, so be it. I'll take happier over thinner any day. Report
Within a year 3 drastic events happened to me. I PLUNGED into a deep, dark depression which meant several hospitalizations hence make it #4 because I could not keep up with my job. A job I LOVED and was very good at. Depression though (plus from the car accident) I was no longer able to work. BINGO GOODBYE to my luxury apt.

I had the WORSE Dr EVER who is HAHAHA Now SUPPOSEDLY in CHARGE of the place. I have NO CLUE why. She kept telling me "YOU TAKE IT OR ELSE I'll PUT YOU BACK INTO THE HOSPITAL!" So I did. SIXTY lbs later on THAT med (Seroquel) the OLD BAT (I weighed 115 at the start at the end of THAT 1 I was at 145!) than she put me on risperdal and BAMB ANOTHER 30 LBS! So UP to 175 in ONLY A FEW MONTHS!! I got SMART and got RID of that old bat!!

I had been talking to someone I had met online and he recommended asking about an MAOI which I did ask my Dr. This is rarely used now since if you eat a WHOLE BUNCH of normal every day food, you can easily have a stroke or heart attack. I AGREED (We did a contract since it can be proved if you accidentally ate an item (often when eating out at any place, including family friends. A friend had a big spread for a bunch of us. THANKFULLY as I went to put the mashed potato into my mouth I thought and asked "What did you put in here?" It was cheese. A NO NO item! PHEW!!) it was necessary for a contract to be done.

In ONLy 3 days I felt so much better! In ONLY 3 weeks I felt as wonderful as I had used to. PHEW!!

If you are ever in a shrinks office, look around. I have. MOST of us where QUITE heavy. It could be that office, but I DOUBT it.

I will say that the MAOI Literally saved my life. I went on to gain and gain. Now it's FINALLY coming off. I've been OFF the MAOI now for almost 2 years an doing very well. Report
Very good advice for those that take antidepressants. Report
Thanks for posting this. I can't tell you how many times as a psych nurse I tried to explain this to patients. For so many, the first and only thing they saw on the medication info sheet was 'possible weight gain.' It's so important to emphasize the benefits of getting depression under control, and to note that every body is different and will react differently. Report
I've been on a bunch of antidepressants, found my appetite increase a bit on ones which were meant to often cause weight loss, and seen my weight slide while on ones supposedly linked to weight gain.

As someone on the other end of the scale, struggling to keep weight on, I know how stressful these changes can be - I can imagine they're as bad though different if you're trying to lose. However, that weight gain is the most depressing thing ever... Try drug resistant anti depressants and the sheer desperation that nothing will ever get better and life will be long term unliveable.

Weight of course affects mood, but to give a physical example, easier for some - my young outdoorsy cousin was diagnosed with leukaemia. The drugs robbed him of the sun and of swimming, made him sick and made him balloon from skinny to pasty and fat. They saved his life. He's now back in the sea, living life, laughing with me.

Meds aren't perfect. They might affect weight. But the side effects won't always affect you, and they are prescribed to you for a reason and can help (or so I'm told, with antidepressants!). Report
I feel so sorry for the person who can think of nothing more depressing than weight gain. How about war, genocide, famine? To think that weight gain is that important, that's pathetic. While I am trying to lose weight and become healthier, it is NOT the end all, be all of my existence. How sad that it is for someone else? Report
Oh, puh-leeze! The person who commented that losing weight is the greatest anti-depressant doesn't have a clue. I'm a behavioral health nurse, have been for 23 years, and I have depression. Anyone who knows about depression will agree that feeling a little heavy is a heck of a lot better than feeling like throwing yourself in front of a big truck. And for some folks, the depression can be so severe that the last thing you want to do is get out of bed, let alone go exercise. Medication can help you get to the point where you can begin to help yourself. Remember, depression isn't a choice or an attitude, it is a medical illness, like diabetes is a medical illness. Report
Sweetie, walk a mile in my shoes, than post a comment about depression. Report
I can think of NOTHING MORE DEPRESSING than taking something that actually CAUSES weight gain. So how can these things possibly work? Losing weight, all by itself, is the best depression-fighter on the planet. So these meds seem like a cruel trick on the people who want HELP. Report
i take wellbutrin, i cant tell it has effected my weight positively or negatively.
doctors should first prescribe diet and exercise, and introduce antidep after the patient has started a healthy program.
physical therapy as well as depression really can lead to physical pain and vice versa. Report
I gained 50 lbs when I started my medication and it doesn't want to come back off. However, mental health care is extremely important and should only be handled by a professional. Going on and off medications should only be done under the supervision and direction of a doctor. No one should encourage people to quit their medicine because of weight gain. It's hard enough to step out against the stigma that goes with being on anti-depressants/anxiety meds without ignorant bystanders suggesting people stop their much needed meds for vain reasons. Sure obesity is harmful to your health, but often so is depression etc... Report
I agree with the commenter who did NOT agree with those who recommend getting/staying off antidepressants. For many of us, it is an actual life saving med. I learned to go back on them when I would notice my overall mood slipping, and that prevented those really bad spells. Afetr cancer treatment, however, and some huge personal losses, I slipped into a horrible depression that went on for two years. Prozac had always worked for me in the past, but did little to help this time. My doctor suggested I try Zoloft, and I agreed, but never expected it to work. I had (and occasionally still have) bad stomach gas and pain the first two weeks - I mean BAD. Anyway, I was desparate, so I stayed on it. !5 days into it, that depression lifted. I have tried Wellbutrin in the past, and that does not work for me, but I have a sister who swears by it. Now I'm on SparkPeople to lose the weight I gained during those horrible two years, but am so happy that that is my biggest challenge now. Good luck to all of you who are struggling - never give up and the answer is probably as individual as you are! Report
my dr put me on Paxil in 2010... and i not only ballooned in my thoracic and abdominal area I haven't been able to take any of it off... I hover around 5 lbs more of less of the weight I've been for the past 13 years even with exercise and appropriate portions... ill never use antidepressants again instead I will concur my depression no matter what and exercise my heart out! Report

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