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11/17/17 6:05 A

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Very interesting so I really should get my brother DNA tested

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11/17/17 5:19 A

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CD7793680 Posts: 13,093
11/16/17 7:11 P

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Understanding Patterns of Inheritance: Where Did My DNA Come From? (And Why It Matters.)

Posted by Anna Swayne on March 5, 2014 in AncestryDNA

Your DNA contains a record of your ancestors, but you arenít a carbon copy of any one of them. The particular mix of DNA you inherit is unique to you. You receive 50% of your DNA from each of your parents, who received 50% of theirs from each of their parents, and so on. In the chart below you can see how the amount of DNA you receive from a particular ancestor decreases over generations. If you go back far enough, there is a chance that you inherited no DNA from a particular ancestor.

The chart below helps illustrate how different segments of DNA might have been passed down from your grandparents to make your unique DNA. Assume each letter represents a segment of DNA. Things to notice are:

1 - Which letters get passed down to each generation is random (the fact that the letters spell names in this example is simply to help with the illustration).

2 - Not all of the letters get passed down.

3 - Just because a child doesnít have a letter doesnít mean that an earlier ancestor didnít have that letter.

4 - Siblings can have different combinations of letters

In the example on the chart, your paternal grandfather has the unique DNA of ANDREW. He can pass down only 50% of his DNA to each child. In your fatherís case, the ďpieces of DNAĒ randomly selected to be passed on to him are represented by the letters DEW. At the same time, grandmother SANDRA provides the randomly selected segments ADR, which combine with her husbandís DEW to create your fatherís unique genetic signature: EDWARD. Notice that not all of the letters from ANDREW and SANDRA get passed down to EDWARD.

Your father, EDWARD, has three children with your mother, whose genetic signature is ANGELA. EDWARD and ANGELA each pass 50% of their DNA, randomly selected, to each of their children, who end up with the genetic signatures GLENDA, GERALD, and REAGAN.

Again, the parents donít get to choose which segments (letters) go to each child. And while having more children increases the chances of passing on more of your DNA, if you look closely, youíll see that even with three children, not all of EDWARD and ANGELAís DNA segments made it to the next generation.

This is a simplified example of how genetic inheritance works in all of us. By understanding how DNA is inherited, you can see how and why you have some DNA segments that match your relatives, and others that do not, why you may or may not have inherited DNA segments associated with a certain ethnicity, and why getting multiple people in your family tested can help discover more of your familyís genetic tree.

I have had fun learning about my own DNA inheritance, especially after I had a few of my family members tested.

Below are 4 sets of DNA ethnicity results from me and my three siblings. Our results are a great example of how genetic inherence is random, just like the letter block example above explains. Do you see how different we are? Focus in on the Europe West ethnicity region between us. If you look at the results on the far right, (which happen to be mine) European West almost doesnít exist. If fact, I would say, in comparison to my siblingís results Europe West isnít being represented at all in my results. But my oldest sibling, (far left) has 32%, next sibling has 5%, and the third one has 16%.

My siblingís DNA results are all different-because we are all different. None of us are twins so we expect our results to be different in some ways. Genetic inheritance is random and my siblingís ethnicity results are a great example of that. But because our ethnicity results are different doesnít mean we arenít siblings. We all show up as Ďimmediateí family in the matching section which is expected. This is why itís important and fun to get others in your family tested. Each of us carry unique pieces of DNA that can unlock our familyís story. If I had just used my DNA results to infer my genetic story, I would have missed out on a few pieces. So itís important to get parents, siblings, aunts, uncles and even 1st cousins tested to help you do more with your DNA results.

Edited by: CD7793680 at: 11/16/2017 (19:12)
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