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5/18/09 8:23 A

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"The UKPDS also showed that Postprandial (blood glucose 1-2 hours after eating) glucose is a better indicator of glycemic control than fasting glucose levels. Treatment of postprandial hyperglycemia is critical to achieving optimal outcomes in type 2 Diabetes.

METHODS:
Sixty-five (65) patients (37male/28 female) completed the study. 7.6%(5) of the patients were insulin dependent. Their pre-study average fasting glucose (163 mg/dl) and postprandial blood glucose (212 mg/dl), and a base HbA1c (8.8) were taken. Patients were instructed to take two (2) tablets per day, one in AM, one in PM for 90 days. They continued to monitor fasting and postprandial blood glucose through the study period. At the conclusion of the 90-day period, their levels were measured.

RESULTS:
Sixty five percent of the participants completed the study. After the 90 days of the Gymnema Sylvestre (Beta Fast GXR) supplementation, mean daily preprandial plasma glucose concentrations were 11 percent lower (161 vs. 144 mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation also lowered the 2-hour postprandial plasma glucose concentrations, by 13 percent (207 vs. 180mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation lowered HbA1c from 8.8% to 8.2% (0.6% decrease).

In the sub set of participants whose pre-study HbA1c was 9% or above the results were more profound. Mean daily preprandial plasma glucose concentrations were 15 percent lower (191 vs. 161 mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation also lowered the 2-hour postprandial plasma glucose concentrations, by 21 percent (250 vs. 199 mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation lowered HbA1c from 10.1% to 9.3% (0.8% decrease).

In the poorest controlled patients, those with a starting HbA1c of 10% or greater, mean daily preprandial plasma glucose concentrations were 18 percent lower (216 vs. 178 mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation also lowered the 2-hour postprandial plasma glucose concentrations by 28 percent (295 vs. 212 mg/dl). The Gymnema Sylvestre (Beta Fast GXR) supplementation lowered HbA1c from 11.1% to 9.9% (1.2% decrease).

In addition 11 patients (16%) had a decrease in prescription medicine "


www.cljhealth.com/science1.htm

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