Being single, I have to buy quantity to get a price break, but end up with too much fresh stuff to use right away. My favorite, Bell peppers, I wash first before cutting, then cut ALL of them up, making sure I have removed ALL the of the seeds. Then I wash them all again, thoroughly. Then I dry them carefully and put them into a ziplock freezer bag. I have been able to keep them in the fridge without spoiling for as long as two weeks!
Why? Nature. The seeds in the pepper are the new life that want to grow into another pepper. So they must take nourishment from the flesh of the old pepper to grow, just like any fruit. So if you get them out of there and clean up after them the flesh won't rot right away!