Although the exact cause of osteoarthritis is not known, some experts believe that joint damage occurs as a response to physical stress (such as injury or repetitive movement). This wear and tear can erode the cartilage, which serves to cushion the ends of the bones in a joint and helps the joint move smoothly and easily. As the cartilage breaks down, the ends of the bones thicken and the joint may lose its normal shape. Eventually, the ends of the bones begin to rub together causing pain and tenderness. The damaged joint tissue can cause the release of substances called "prostaglandins," which further contribute to the pain and swelling associated with osteoarthritis.
There are two main categories of risks that can contribute to osteoarthritis—those that you can't change, and those that you can. Continued ›
The Causes of Osteoarthritis
Learn Which Risk Factors You Can Control
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