Treatment of candidiasis varies, depending on the area affected:
Thrush — Doctors treat thrush with topical, antifungal medications such as nystatin (Mycostatin and others) and clotrimazole. For mild cases, a liquid version of nystatin can be swished in the mouth and swallowed, or a clotrimazole lozenge can be dissolved in the mouth. For more severe cases, fluconazole (Diflucan) can be taken once a day by mouth.
Esophagitis — Candida esophagitis is treated with an oral anti-fungal drug such as fluconazole.
Cutaneous candidiasis — This skin infection can be effectively treated with a variety of antifungal powders and creams. The affected area must be kept clean and dry and protected from chafing.
Vaginal yeast infections — Vaginal yeast infections can be treated with antifungal medications that are applied directly into the vagina as tablets, creams, ointments or suppositories. These include butoconazole (Femstat), clotrimazole (Gyne-Lotrimin), miconazole (Monistat, Vagistat and others), nystatin (Mycostatin and others), and tioconazole (Monistat-1, Vagistat-1). A single dose of oral fluconazole can be used. Sex partners usually do not need to be treated.
Deep candidiasis — This infection is usually treated with intravenous fluconazole. People with very low white blood cell counts may need an alternative intravenous anti-fungal drug, such as caspofungin or micafungin.