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Health A-Z

Medical Content Created by the Faculty of the
Harvard Medical School

Symptoms

Early signs and symptoms of Tay-Sachs disease can include:

  • Loss of muscle tone

  • Exaggerated response to sudden noises

  • Lack of energy

  • Loss of motor skills, such as the ability to roll over, crawl, reach for things or sit up

In its advanced form, the disease causes a gradual loss of vision, deafness, seizures, gradual paralysis and dementia. Red spots may appear on the retina (inside the eye).

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From Health A-Z, Harvard Health Publications. Copyright 2007 by the President and Fellows of Harvard College. All rights reserved. Written permission is required to reproduce, in any manner, in whole or in part, the material contained herein. To make a reprint request, contact Harvard Health Publications. Used with permission of StayWell.

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