Scleritis needs to be treated promptly to help avoid complications and vision loss. When related to an underlying disease, treatment of the disease may control the inflammation of the eye. Drugs used to treat scleritis include a corticosteroid solution that you apply directly to your eye, an oral corticosteroid (prednisone) and a non-steroidal anti-inflammatory drug (NSAID). More powerful medications that suppress the immune system may be needed for severe cases not responding to corticosteroids. In severe cases, surgery may be required to repair injured areas of the eyeball.