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Symptoms include:

  • Pain, swelling, limited motion, warmth and tightness around affected joints, which most commonly include the hands and wrists, feet and ankles, elbows, shoulders, neck, knees and hips, usually in a symmetrical pattern. Over time, joints may develop deformities.

  • Fatigue, soreness, stiffness and aching, particularly in the morning and afternoon (described as morning stiffness and afternoon fatigue)

  • Lumps or rheumatoid nodules below the skin

  • Weight loss

  • Low-grade fever and sweats

  • Trouble sleeping

  • Weakness and loss of mobility

  • Depression

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