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Expected Duration

People often recover within two to six weeks without antibiotics. Even Lyme arthritis often improves on its own as the body's immune system attacked the infection, although it's common for it to return. Antibiotic therapy is highly effective at curing the illness. Significant improvement occurs within two to six weeks after beginning therapy.

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From Health A-Z, Harvard Health Publications. Copyright 2007 by the President and Fellows of Harvard College. All rights reserved. Written permission is required to reproduce, in any manner, in whole or in part, the material contained herein. To make a reprint request, contact Harvard Health Publications. Used with permission of StayWell.

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