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MS_AISHA's Photo MS_AISHA Posts: 56
7/9/09 1:06 P

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Hi I just started taking Metformin yesterday,well I am a Nuring student and I always read FINE print..lol...I just want to share with you what it said about PCOS.
" It is also used in women with a certain disease of the ovaries (polycystic ovarian syndrome). By helping your body to respond better to insulin, Metformin may decrease the risk of diabetes, make menstrual cycles more regular and increase fertility." The was good enough for me, my doc also has me test my blood sugar twice a day and put me on a diet with at least 130 carbs a day a no more then 144 carbs. He gave me a booklet to write everything down and wants me to see him every 3 weeks. He did say the Metformin with help the way my body reacts to carbs and in turn helping me lose weight, he said it wont be fast but it wont be crazy slow, just be patient and dedicated. He is the best, this is all new to me..and I was crying in his office. He just gave me a hug and said "You are to pretty to let this thing take over your life,you can beat this"... I really needed to hear that...sorry for babbling...lol

"God Never Gives You More Then What You Can Handle"

Name Aisha
Age 30
Height : 5 ď2
Start Weight 207 lbs
Goal Weight 130 lbs



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VALLEEGURLIE916's Photo VALLEEGURLIE916 Posts: 13
6/17/09 11:06 P

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Thank you all for your feedback. I have to say I didn't notice any side effect really until I took a full dose 1500mg a day. That first night I was so nauseous I couldn't sleep. Happy to say that since then Its just been minor cramps and one or two episodes of diarrhea. I'm convinced the weight loss and excessive sweating im seeing is in due partly to the Metformin. I'm willing to stick with as long as I don't experience anything very serious. Im not so concerned about ovulating. Working in labor and delivery has made me a little wary about having children right now. =)

Edited by: VALLEEGURLIE916 at: 6/17/2009 (23:06)
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DANGIELI's Photo DANGIELI Posts: 5
6/17/09 5:04 P

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Metformin's side effects are mostly GI. Abd cramps, bloating, diarrhea, nausea...etc. Whether you take if for PCOS or Diabetes, the side effects are the same. That being said. I never had abd pain and diarrhea until I started taking the Metformin 500mg twice a day. I then moved to Metformin ER 750mg 2 a day. I have found my symptoms have lessened, but not disappeared. I did go for 6 months last year not taking it, my abd pain and diarrhea went away, and I gained a ton of weight. I was back to 360#. My max was 384# 5 years ago. Needless to say, I went back on it. So far I am down 24#. Easy to gain, hard to loose. But I am doing it!! And I will be taking the Metformin and sucking up the side effects because I so badly want to be healthy and get pregnant again. Because it decreased insulin resistance, it helps us ovulate. And I need that.

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CLES26's Photo CLES26 Posts: 7
6/14/09 8:54 P

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I have been on Met since October. I have found it to really cause GI problems if i eat too many vegetables in the day. My friend told me too many leafy greens caused her problems, and it bothered me too. Lately instead of salads i would make a plate full of carrots, celery and cucumber, and within a day or two i experience the worst stomach pains imaginable. I end up spending hours in the bathroom. this has happened a few times and only since being on Met. The side effects can be different for everyone though. I have found it helpful in decreasing my appetite too...and its helped me to lose weight, my ENDO said, many women with PCOS seem to experience this.

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SOUTHERNMEL's Photo SOUTHERNMEL SparkPoints: (36,480)
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6/14/09 8:36 A

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Type II diabetics are insulin resistant as well as have trouble with keeping a normal blood glucose level (type II manifests after years of being insulin resistant). Anyone with insulin resistance (no matter if you've gone so far as to become diabetic) can benefit from taking an oral anti-diabetic if diet and exercise haven't worked to reverse the condition and bring things back to normal. Any type of GI discomfort (nausea, gas, diarrhea, constipation) can occur. It is typically worse when your meals are high in simple, processed carbs and/or fat. The constipation comes from introducing too much fiber at one time because most people try to eat better while taking it to avoid some of the other issues. If you've had a very low fiber diet, slowly increase your fiber intake each week to 25-35g a day. That will help. My personal experience is that if I don't eat at regular intervals, then I get very shaky & dizzy (I didn't have this problem before). I had the nausea for the first 4-5 weeks (it diminished each week) I took it. Until I found the right time to take it for me, I did have GI issues. I found that it was best for me to take it about 1-1.5 hrs after dinner. If I'm queasy to begin with, then I take it with a glass of milk which helps with any additional side effects I might have.

As to the weight loss, metformin isn't designed to produce weight loss. It can help those that are active and because of insulin resistance are having trouble losing weight. Weight loss isn't guaranteed. The most important thing is that your insulin levels are in control and within the normal range, and you don't progress to being diabetic. You'll still have to carefully monitor your diet and get regular exercise.

Melissa Nestor, MS, CSCS


"Choose a good reputation over great riches; being held in high esteem is better than silver or gold."

Proverbs 22:1, NLT


"A cheerful look brings joy to the heart; good news makes for good health."

Proverbs 15:30, NLT





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VALLEEGURLIE916's Photo VALLEEGURLIE916 Posts: 13
6/13/09 5:38 P

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I have was recently prescribed Metformin to help regulate my insulin spikes after meals and from what I understand it is usually prescribed to diabetics. I was just curious what side effects I may expect other than nausea. Also I was curioius to know what type of changes in wieght loss i might expect?

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MAL5W_ANN's Photo MAL5W_ANN Posts: 157
4/13/09 11:27 A

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For me, one of the things about the ER was that I could tolerate a much higher dose of metformin than when I was on the regular. The regular stuff made me nauseated all the time - even on a lower dose (750 mg twice a day).... my doc recommended taking the whole ER dose (2000 mg) with dinner, but even THAT made me too nauseated to sleep... so I've divided it up to 1000 mg in the morning and 1000 mg with dinner. i feel like it has helped regulate my system better.

"I am careful not to confuse excellence with perfection. Excellence, I can reach for; Perfection is God's business"



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QTPIE8422's Photo QTPIE8422 Posts: 76
4/11/09 11:27 P

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OK, I guess that makes sense. I wasn't thinking of the insulin resistance with PCOS. I was just thinking treating strictly the PCOS it wouldnt do much. But it would def help with the insulin resistance. And I know about the struggling to get pregnant. My mom also has PCOS and she calls me her miracle baby since she struggled to get pregnant. That is what scares me cuz I want to have a few kids, but when I go off birth control I never have a period. So I'm afraid when I am ready to get pregnant I won't be able to.

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BIGCHESNEYFAN's Photo BIGCHESNEYFAN Posts: 74
4/11/09 11:16 P

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Actually there are MANY people that are taking Metformin for PCOS. It's not just to regulate your period. Many are taking this because they are Insulin Resistant which keeps them from being able to take off any weight at all. Metformin improves the cellís response to insulin, and helps move glucose into the cell. As a result, your body will not be required to make as much insulin. Also, many women with PCOS can't take birth control because they are trying to get pregnant which is a problem with having PCOS and this helps to get their periods regular. It also can help some with lowering their testosterone level which causes so many other problems.

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QTPIE8422's Photo QTPIE8422 Posts: 76
4/11/09 10:47 P

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That is very weird that your doctor prescribed metformin for PCOS. I am a pharmacy student so I am learning about all these meds and I have never heard of that before. Metformin is generally used for type 2 diabetes and can help with weight loss a little. I also have PCOS and I am just on birth control to keep my cycle regulated.

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GMEISSNE1's Photo GMEISSNE1 Posts: 121
4/6/09 7:00 P

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I would be very concerned that your doctor prescribed Adderal for weight loss. It is highly addictive, and can be bad for your heart. I take it for ADHD and I have to be sure to drink no caffeine, and to get an EKG every year to make sure it isnt affecting my heart. I also dont take it on weekends or over vacations from school, so that I dont become addicted.

It is most definitely the Adderall that is making you lose the initial weight. It decreases hunger, and speeds up your metabolism. Unfortunately, as most of us who take it for ADD know, the weight loss isnt easy to maintain when you arent taking it, because you havent learned any better eating habits, you just werent hungry.

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SOUTHERNMEL's Photo SOUTHERNMEL SparkPoints: (36,480)
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4/3/09 10:14 P

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Metformin ER is time release medication. Instead of dumping the whole thing into your system as soon as your body digests it, the ER version releases slowly over time. It can be easier on the digestive system and can decrease the number of times you take the pill. Simply put, you can take just 1 dose and the medication will release over the next 12-24 hours, rather than taking a dose with each meal. If you are on the higher end of the dosage scale, the ER is more convenient to take.

I'm guessing your recent weight loss is probably due to Adderall since it's a central nervous system simulant (it's an amphetamine and dextroamphetamine...think prescription Dexatrim). The Metformin may be helping, but if you were on it before and were just switching to the ER, then the weight loss is probably more of a result of the Adderall.

Melissa Nestor, MS, CSCS


"Choose a good reputation over great riches; being held in high esteem is better than silver or gold."

Proverbs 22:1, NLT


"A cheerful look brings joy to the heart; good news makes for good health."

Proverbs 15:30, NLT





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BIGCHESNEYFAN's Photo BIGCHESNEYFAN Posts: 74
4/3/09 12:53 P

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I was diagnosed with PCOS a few years back and my doctor put me on Metformin and gradually increased me to where I am now taking 750mg ER twice a day. Prior to last month I was taking 750mg not the ER. Has anyone seen better or worse results with ER vs the regular? It doesn't make me sick when I take it so I'm not concerned about that since I have taken both types. Thanks for your help.


Edited by: BIGCHESNEYFAN at: 4/6/2009 (20:44)
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