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FOURREDONEBROWN's Photo FOURREDONEBROWN SparkPoints: (22,172)
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4/23/09 12:10 P

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Hi everyone! I'm Amanda, and I'm new...
Metformin has been an absolute God-send to me. I've been taking it for nearly 5 years. Like someone else said, I lost a great deal of weight at first (around 20 pounds). The side effects were bad at first, and I switched to Glucophage but after a while I went back to metformin and had no trouble. The weight-loss is secondary, though. The best part of taking metformin has been the way I feel. I don't carb-crave like I used to, and I don't get the shakes after I eat. My periods used to be sporadic at best, whereas now you can set your watch by them. I highly recommend that you stay in regular contact with your endo, and be patient with the process.
Good luck!
Amanda

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ELLE4308's Photo ELLE4308 Posts: 833
4/23/09 11:05 A

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metformin didn't really help me lose weight either (sometimes the side effects did though-but that was NOT pleasant!) I'm now on Byetta as well, and I'm losing but VERY slowly, I feel like with PCOS it is just determination and good choices that'll do anything, even when coupled with these drugs.(apparently byetta helps diabetics lose loads of weight)

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MEGSED's Photo MEGSED Posts: 181
4/22/09 4:32 P

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I've gained weight since starting metformin. It could be in part to the bcp they started at the same time but I've been off the pill for over a month now and my weight has just stayed at where I gained to. Metformin is not a miracle weight loss drug for everyone.

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YAXFAMILY's Photo YAXFAMILY Posts: 9
4/21/09 9:45 P

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I just started metaformin friday night and I was wondering how long it took any of you to feel better or start losing weight? Also did it seem to make the weight loss easier? I can workout and eat good for a week and the scale won't move an inch!

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IVYWANDA's Photo IVYWANDA Posts: 48
2/4/09 11:24 A

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Thanks! I am still losing weight, of course not as quickly but we will see at the end of the week. It definitely makes you aware of what you are eating, because you don't want to have an episode.

He who risks nothing, does nothing, has nothing, is nothing, becomes nothing. True wealth is the ability to fully experience life! Take a risk! Enjoy life! :)
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ELLE4308's Photo ELLE4308 Posts: 833
2/2/09 11:13 A

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I swear, it is really frustrating how doctors don't share important info. I got that last tidbit from a nutritionist, a week after a doctor told me metformin doesn't help at all with weight loss. Um? preparing my body to process sugars, how does that not help at least a little bit?

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JPCHICAGO Posts: 58
2/1/09 6:56 P

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Congrats on the 7 lb loss, Ivywanda!

TOMMIEHANNAH's Photo TOMMIEHANNAH Posts: 88
2/1/09 1:50 P

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Well, that ticks me off....I was told that if it upset my stomach I could take it before I went to bed (which is usually hours after I have eaten!!) But I've been on it since June 2008 and haven't lost a single pound!! I'm trying it your way. I'm also going to try to get in touch with my endo this week...

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ELLE4308's Photo ELLE4308 Posts: 833
2/1/09 1:09 P

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I've been on metformin and i have lost and not lost on it. I met with a nutritionist and she explained metformin the best of anyone. Metformin prepares your body to properly injest the food. If you don't take it prior to a meal, she said, not to bother because then it won't do anything. Now I take it within an hour before breakfast and the same for dinner. I've been doing ok losing weight this week (since I started using it correctly)

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IVYWANDA's Photo IVYWANDA Posts: 48
2/1/09 10:26 A

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Thanks! it's been one full week and I feel much better. I am down to one episode a day and can deal with that. I lost 7lbs this week.

He who risks nothing, does nothing, has nothing, is nothing, becomes nothing. True wealth is the ability to fully experience life! Take a risk! Enjoy life! :)
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WONDERJANE's Photo WONDERJANE SparkPoints: (12,272)
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1/30/09 1:15 P

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when I started on met my endocrinologist started me at 500 mg once a day for two weeks, then twice a day for two weeks then three times a day - and recommended that I take it with a no or very low-carb meal. It worked for me to minimize the gastro-problems. Now I have occasional naseau, usually in the morning if at all, and tolerate it very well. I see a difference in my complexion and feel a difference in the stability of my blood sugar when I am taking it regularly, so I am willing to put up with a bit of tummy trouble.

Courage is not the absence of fear, but rather the judgment that something else is more important than fear.


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JPCHICAGO Posts: 58
1/29/09 6:45 P

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It seems to me like your doses are increasing very quickly, but I am not a doctor. I think I typically stayed on lower doses for 2 weeks or so before I got comfortable with them and my doc increased to higher levels.

One other suggestion I forgot to mention earlier --- I had better success with the GI issues when I started when I took Met not only at meal time, but took it right in the middle of my meal - so some food was already in my stomach, & more was going in to surround that pill! Could be more psychological, but it made a big difference to me when I was first battling the side effects of Met.



IVYWANDA's Photo IVYWANDA Posts: 48
1/29/09 1:46 P

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1 pill twice a day 500mg. The first two days I only took 1. One the 3rd day i took both.

He who risks nothing, does nothing, has nothing, is nothing, becomes nothing. True wealth is the ability to fully experience life! Take a risk! Enjoy life! :)
-Rev Run


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JPCHICAGO Posts: 58
1/27/09 9:02 P

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Ivywanda - It does get better. It took me about 2 weeks to adjust when I first started taking it. I had to be very good about eating a decent sized meal (not just a snack) when taking the met and also make sure it was not heavy in carbs to get over the digestive problems. What dose did you start with? That also makes a big difference - you need to start low and slowly build up.

IVYWANDA's Photo IVYWANDA Posts: 48
1/27/09 11:28 A

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I just start metformin on friday,and I can barley tolerate eating or drinking anything. Does it get any better? I have lost a couple of pounds since Friday already, but is it worth it? I am MISERABLE!


He who risks nothing, does nothing, has nothing, is nothing, becomes nothing. True wealth is the ability to fully experience life! Take a risk! Enjoy life! :)
-Rev Run


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JPCHICAGO Posts: 58
1/11/09 2:51 P

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I have been on Met for almost 4 years. When I initially started it, I lost a significant amount of weight in a a relatviely short period of time...a 15 - 20 pound loss. I have had to change my eating habits on met. I absolutely need to eat breakfast, and I eat 5 - 6 smaller meals throughout the day instead of 2 or 3 larger ones. Taking Met with a meal helps combat the GI issues.

I think Met did help regulate my periods somewhat and in combinations with BCP and Spiro, helped combat some of my other PCOS symptoms.

LETIA659's Photo LETIA659 Posts: 18
10/31/08 2:54 P

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I definatly gained weight on metformin and as soon as I quit taking it I lost quite a bit of weight. I just got the ok from my doc on not taking it anymore she said that seeing as Im eating healthy and exercising and loosing weight that she didnt want to put me back on it. I have heard a lot of people say it does help them lose so I guess its affects are different on different people the only way to know is try it but I just couldnt handle the side effects of it even the XR...

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KATIALYNN's Photo KATIALYNN SparkPoints: (5,704)
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10/27/08 5:57 P

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I think I lost more off it than on it too. I had a miscarriage in February and for about 2 months was completely out of sync - didn't take my met., didn't work out, ate whatever crossed my path, but still managed to lose weight. It was really bizarre. Then when I started taking it again, and watching what I ate, I went back to my pre-weight loss weight... No explanations from the doc. She just attributed it to stress.

Dum Vita Est, Spes Est - While there is life, there is hope.

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TEACHERRJD's Photo TEACHERRJD Posts: 438
10/18/08 12:47 P

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I've used metformin for years, mainly to help me get pregnant and stay pregnant. I've taken up to 1500 mg of extended release. I do better on XR than on regular. I did have some gastric side effects to start with, but they went away on XR. It did not help me lose weight, even though the pharmacist said it would. In fact, I think I am losing more off it than on it.

Rachelle, mom of two.


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XJXWXM's Photo XJXWXM Posts: 252
10/17/08 3:36 A

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I had an allergic reaction to metformin one week after I started using it last year. I don't take anything now but I recently started using cinnamon again.

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MAMAPETE3's Photo MAMAPETE3 SparkPoints: (88,632)
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10/1/08 5:00 P

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I was on Metformin for a couple of years. I did lose a little weight and had gastro issues in the beginning. I was on 500mg a day and tried to up it to 1000 but I couldn't handle it. Had to quit taking it this summer due to having a colonoscopy. While I was off of it, I discovered that I felt sooooo much better. Not in a fog anymore and feeling like a human again. So I no longer take it. I have changed all my pasta and bread to whole wheat, cut out sugar and cut out caffeine and upped my exercise.

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GAJEN2345's Photo GAJEN2345 Posts: 300
9/13/08 6:32 P

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I have been on metformin for a year and a half. I am taking 1000mg twice a day. When I first started taking the Metformin I did have some major GI problems. I finally had to find out what food seem to upset my stomach more than other. I also talked to my doctor; he suggested instead of taking it in the morning and evening, to take it at lunch and dinner. He stated that many people don't eat enough in the morning for the metformin not to cause some discomfort. Since I changed up on the times when I take the metformin I have had only a few GI problems. I have lost 47 pounds since starting the metformin.
Finding a good doctor is very important with finding what works best for you. It took me several years to find a doctor that was willing to run test and find out what works best for me. This doctor is also familiar with PCOS. What works for one may not work for all.

Jennifer


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KITTYKITTEMMING's Photo KITTYKITTEMMING SparkPoints: (80,917)
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9/11/08 11:08 P

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Actual side effects of Metformin are mostly in the gastrointestinal area. Many have frequent diaherrea, some nausea. I have been on Metformin for about two weeks with few troubles, just a few Metformin Moments of unexpected diaherrea. I'm kind of working on a hypothesis that some of those problems are related to eating too much of a food group, like fats.

Heather
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JWOURMS's Photo JWOURMS Posts: 750
9/7/08 4:00 A

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I've been on Metformin for 4 weeks and have already lost 2.5KG. I'm very happy with this weight loss, before Metformin, I'd been dieting for a month and had only lost 1/2 a pound.
My understanding from my physician is that taking metformin can be preventative, potentially stopping diabetes. My body was over producing insulin and if it kept doing so it would eventually exhaust itself and not be able to produce ANY insulin. Voila Diabetes. By taking the Metformin the tissues in my body are more responsive which means by body doesn't need to produce so much insulin. Given the side effects of diabetes (a friends father just had a very nasty prolonged death from the disease) and the side effects from Metformin. I'll take Metformin thanks.

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HERALD2 Posts: 4
8/31/08 1:56 P

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Ayurveda treatment is very good for PCOS. It has a holistic approach and will reduce the weight. It believes in basic correction of metabolic functions so that the body will be rejuvenated with the treatment. Hyponidd is an ayurvedic formulation which can be used instead of Metformin. You can read more about it in www.ayurvedaforall.com/1076/hyponidd
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ablets.html


CFALLIN's Photo CFALLIN SparkPoints: (0)
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8/26/08 2:03 A

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thanks for your reply. ooh that point about the what do you do if you get diabetes thing is a little scary and something I never considered. What side effects did you have from the metformin?

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IVORY1825's Photo IVORY1825 Posts: 7,702
8/25/08 10:57 A

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I have been on the lowest dose (500mg/day) of metformin for over a year. Prior to being on it, I would also get hyopglycemic if I didn't eat. Since being on it, I have been able to lose weight and feel better about not bouncing between high and low blood sugar. On the met, you are able to more effectively use the sugars from your meal, so your insulin doesn't spike as high, therefore, you won't get hypoglycemic as easily. I only have problems now if I try to do heavy activity too far away from a meal. If I'm just going about normal activities, I can space my meals farther if needed. I used to need to eat every 2-3 hours, now I can easily manage 4-5 hours. However, if I am going to workout, I always make sure I've eaten something whole grain and protein balanced no more than an hour before. I love metformin, and have lost 40 lbs since being on it. However, I also maintain a low GI diet and try not to eat simple carbs or sugars so that I don't further aggravate the problem and can hopefully maintain this level of medication (and no more) for a very long time (I'm 26).

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SANDRASPEAKS's Photo SANDRASPEAKS Posts: 1,118
8/25/08 6:00 A

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Hard to tell what it would do to you...but if you have times of the day when your sugar is low, you would have to be careful or you could blackout/passout due to low sugar levels.

The only question doctors can't answer is if you take a large dose of metformin now for PCOS, what happens if you ever do get diabetes? Most can't answer that. The answer probably is that you would have to go directly to shots if you ever got diabetes.

I couldn't handle the side effects on met...so I'm trying to cut carbs and sugars to lose weight. It hasn't been easy but I have lost almost 30 pounds since March.

My only caution is --find a doctor who cares about fixing YOU...and start with a low dose and work your way up. Normally they start you too high and then after side effects, they will lower it.

Hope that helps.


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8/25/08 5:24 A

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I have PCOS... I was told metformin would help alleviate my symptoms and to lose weight. I do not have diabetes but have failed the insulin resistant 4 hr test but frequently I have fasting Hypoglycemic episodes if I miss a meal or do not eat enough carbs. Would Metformin cause me to lose weight? Would it cause me to have more frequent episodes of low blood sugar?

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