Numbness is not one of the posted side-effects, but I know several people with both diabetic and PCOS diagnosis, who have mentioned it. Not so much in there thighs, but its there!
My husband is a pharmacist, and so when I was prescribed it, he explained that Metformin is designed to "open the gates" of your cells, so to speak. With Insulin Resistance, your cell walls are kinda closed off, they won't accept the insulin, and so Metformin acts to regulate all kinds of resistances - including hormone resistance, which is the hall mark of PCOS.
Good Luck with your Doctor!
Edited by: BEATLES_67 at: 9/16/2010 (12:32)
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