Posts: 9
9/11/12 11:27 A

I participated in a inhaled insulin research study. I didn't even make it through the trial. The simple fact that they only had 2 doses which in unit terms equalled 3units or 9units, or you could combine them for 12. Really? 3units is way to much for me most of the time. I ended up gaining weight from trying to keep my blood sugar up.... of course by eating enough to meet the 3 units. I was not impressed and it didn't take too long before I said thanks, but no thanks. That was even before the lung cancer issue was brought up.

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4/12/08 4:15 P

No, I have not read that one yet.

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4/11/08 7:32 P

GG, I had no interest in the inhaled insulins either. I have lots of allergies and the idea of inhaling something into already sensitive sinuses never excited me! The lung cancer risk makes it even worse!

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4/11/08 11:22 A

2) Elevated Lung Cancer Cases in Users of Inhaled Insulin

You know I'm really not surprised by this one. We know that insulin cause hypertrophy of fat cells. Imagine what it will do to the delicate lung cells. When non-diabetics asked if I was excited about the inhaled insulin I always said "no!". When I told them it is no longer on the market because of lack of interest, the non-diabetics usually say that it's too bad because it would be a great alternative for people who don't like shots.

So really now is lung cancer a great alternative enduring needle sticks and a flabby belly?

I always found it strange that non-diabetics think they know what's best for us better than we do.

Sorry I didn't mean to jump on a soap box. I'll step down now.

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4/10/08 11:10 P

man I had a big day at work today and so i skipped right over that thank you for posting it is very intresting

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4/10/08 6:48 P

Those were very interesting, thank you!

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4/10/08 5:56 P

Did you guys read these articles in the SP health news?

1) Intestinal Nerves May Play Role in Blood Sugar Control

Canadian researchers have found that the intestines play a major role in controlling blood sugar levels, a discovery that could help in efforts to create safer and more effective diabetes medications, the Toronto Star reported.

The University Health Network team's tests on rats revealed that a set of nerves in the intestines is intimately involved in controlling blood glucose levels. This cluster of nerves senses the presence of food and signals the brain to halt the liver's glucose production. But the researchers found that a high-fat diet can switch off this signaling system, the Star reported.

"The cure for diabetes is to lower blood glucose levels... and this will be an innovative and effective approach to do that," said study senior author Tony Lam, the Star reported.

He noted that the gut can access drugs directly, instead of having to rely on blood for drug delivery. This finding about the role of intestines in controlling blood sugar levels could make it easier to create drugs to correct blood sugar problems.

The study was published in the journal Nature.


2) Elevated Lung Cancer Cases in Users of Inhaled Insulin

Patients who used the inhaled insulin product Exubera had an elevated number of lung cancer cases, drug maker Pfizer Inc. disclosed Wednesday. The lung cancer cases were discovered in an analysis of clinical trials and post-approval reports to Pfizer and the U.S. Food and Drug Administration, Bloomberg news reported.

All the patients who developed lung cancer "had a prior history of cigarette smoking" and "there were too few cases to determine whether the development of lung cancer is related to the use of Exubera," Pfizer said in a statement.

Last October, Pfizer stopped selling Exubera, which failed to catch on with patients and doctors due to its cost and cumbersome delivery device, Bloomberg reported.

In addition, the inhaled insulin seemed to decrease lung function, apparently due to the way the insulin was delivered into the lungs, Forbes reported at the time.

current weight: 148.0

186 174.5 163 151.5

140