I personally do not know about Reclast only what I have read:
Zoledronic acid is a drug used as a once-a-year osteoporosis treatment. It was approved by the Food and Drug Administration in August 2007 for treatment of osteoporosis to coincide with the study released by the New England Journal of Medicine .
It is currently being marketed under the brand name Reclast by Novartis Pharmaceuticals. According to the Mayo Clinic, it works by slowing the breakdown process of a woman's bones, which typically speeds up after menopause due to decreased estrogen.
Invented by researchers at the University Clinic of Dusseldorf Germany in conjunction with researchers from the 'Westdeutsches Osteoporosezentrum' at the 'Klinikum Leverkusen', Germany.
The three year German study involving 7,700 postmenopausal women. During the first year of the study, researchers say there was a 70% reduction in spine fracture. Furthermore, all patients showed improvements in their bone density. IT is said to also reduce the number of new hip fractures.
Patients taking Reclast will also need to take vitamin D and calcium, they added, and some will experience flu-like symptoms which can be alleviated with a non-steroidal anti-inflammatory drug.
The once-a-year dose obviously is attractive," said Dr. Stephen Honig, director of the Osteoporosis Center at the New York University Hospital for Joint Diseases. "This combination makes it potentially a very important drug. The caveat is the potential side effects. Other studies have found atrial fibrillation."
During the study of zoledronic acid as a once-a-year osteoporosis treatment, patients who received the drug rather than a placebo showed a higher incidence of abnormal heart rhythm . Fifty women in the group being treated with the drug had this problem, compared to 20 women in the placebo group. However, researchers say this number is not statistically significant and does not indicate that the drug is dangerous. The issue of atrial fibrillation is important and will mean the patients need to be warned and monitored.
They also found no reports of osteonecrosis of the jaw, a painful jaw condition, which had previously been associated with this class of drugs.
¸.´ .´¨¨))May you have Butterfly Mornings and Wildflower Afternoons!
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-:¦:- ((¸¸.´* Dusty
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