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NANCYJACK Posts: 4
5/26/10 8:16 A

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Here is another medicine named generic indocin used to treat gouty arthritis. You can find the details at www.internationaldrugmart.com/indoci
n.
html


Edited by: NANCYJACK at: 5/26/2010 (08:16)
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11/19/08 9:24 P

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Another news article about a medication for gout. (It is a different article from the one I posted below.)

www.sparkpeople.com/resource/health_
ne
ws_detail.asp?health_day=620653


Edited by: JANEXA at: 11/19/2008 (21:25)
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9/6/08 1:19 A

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News article from SP about a new medication for gout.

www.sparkpeople.com/resource/health_
ne
ws_detail.asp?health_day=619057


Edited by: JANEXA at: 11/19/2008 (21:24)
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7/19/08 10:50 P

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Here's some info about dairy and gout:

www.arthritis.org/milk-good-for-gout
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Milk is Good for Gout


There’s a new diet in town – and people with gout may be surprised. A study in the New England Journal of Medicine reports that milk and other dairy foods, as well as certain purine-rich vegetables, don’t contribute to gout.

The research, part of the Health Professionals Follow-up Study, found that drinking milk could actually reduce a person’s risk of developing gout by as much as 43 percent. Beans, peas, mushrooms, spinach and cauliflower, all on the gout blacklist because of their high purine content, were exonerated by the study, which found they did not appear to be a factor for developing gout.

The study did support the traditional prescription to limit red meat and seafood – an extra portion of meat each day increased the risk of developing gout by 21 percent, and an extra serving of seafood raised the risk by seven percent.

(Arthritis Today, July - August 2007)


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7/17/08 10:48 A

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emoticon
The Dr.gave me stretching exercises for it,and they help.

How about you,Ms.Janet- how is your hip?

Sandy emoticon

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7/16/08 9:21 P

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Happy to hear it is not as painful as gout, and not happy to hear there is something else going on with your foot. ugh.... It has to end sometime, Sandy, and I'm glad you are keeping your spirits up in spite of it all.

emoticon

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7/14/08 11:36 A

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For crying out loud...now the Dr.says that I have plantar fascitis. I thought maybe it was residual gout. It's in the sole of my foot. I call it a heel spur. At least it doesn't hurt as much as gout!

Sandy

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7/7/08 12:52 P

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My diabetic kidney disease has progressed. That's why I got the gout...my kidneys are not able to process the uric acid. The only symptom that I have is EXTREME fatigue,and that won't be every day. I ordered a book that should help me understand what's happening in my urinary system,and to prolong the inevitable dialysis. The diet is really weird,but I'll get used to like I did with the diabetec diet.

Sandy emoticon

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6/25/08 2:20 A

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Sandy, the doctor who answered the questions really did not address this person's concerns for his dad. It was such a non-answer to this question, and the doctor pretty much said that it was up to the person's dad's doctors on how to treat him. Unbelievable! I understand that the doctor responding could not give much advice since he had not seen the dad, but come on, he (the doctor) barely gave any kind of response. Really annoying, and how sad for this person and his dad that no one was/is answering the questions and concerns expressed.

I guess patients must now have to be very, very assertive in getting their questions answered AND getting treatment that is desperately needed for gout. It seems like there is not enough information available for doctors or patients about how to deal with this problem.

Based on Joe's experience and Sandy's, it seems like every person's gout is different, and has to be treated differently--especially with someone who has multiple medical conditions. I have deep respect for all of you who have gout and have to face such pain and lack of medical focus on treating gout.

It almost makes me want to become a medical researcher!

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6/24/08 4:42 P

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Seems like...gout and gouty arthritis are used inter-changeably. I thought that the arthritis wasn't supposed to appear until you've had gout for several years?

I think I'm seeing the big picture. Can acute gout attacks cause the joint deformities,even though you don't have the gouty/metabolic arthritis? Is it common to have repeated episodes on & off for a couple of months?

Is the arthritis treatment protocol any different than for gout? One more thing- does anybody have tophi? If so...where? And does it just visit or take up residence permanently? I'm tired of reading article after article.

But the good news is...my feet are better. I think it has something to do with wearing my compression socks,but I can't back up the theory. Some of the symptoms were due to the chronic fluid retention in my feet and ankles.

Signed,
The Question Lady emoticon

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IT*SNEVER2LATE's Photo IT*SNEVER2LATE Posts: 4,026
6/18/08 8:37 P

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What a huge injustice to this poor,misdiagnosed,gentleman who is in jeopardy of losing his pension at the age of 62,due to the blundering medical profession! Read on...


www.hopkins-arthritis.org/ask-the-ex
pe
rt/gout-pseudogout-other-009/gout-atR>tacks-increasing-due-to-996.html


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6/15/08 8:13 P

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Is it gout,or isn't it? I've been complaining of pain on the inside of my knee. I do have osteoarthritis,but it feels different than usual. This afernoon,I walked into the kitchen,and turned to reach for something,and I couldn't lift my leg off of the floor. I walked sideways,like a crab,dragging my foot to the bedroom to get my cruthches. I kept telling myself that my pain was due to the change in my gait due to the gout in my foot,but can you get gout in your knee? I am still on 30 mg.of Prednisone,and was planning to taper off of it starting Tuesday. If this pain keeps recurring,I will probably need to call the Dr. tomorrow. Gout SUCKS!

Sandy

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6/13/08 11:35 P

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I found it interesting that the definition stated that gout may attack internal organs,especially in the digestive tract. Has anybody experienced that (JOE?)
____________________________

Definitions of: gout
Definition: A drop; a clot or coagulation.

Definition: A constitutional disease, occurring by paroxysms. It consists in an inflammation of the fibrous and ligamentous parts of the joints, and almost always attacks first the great toe, next the smaller joints, after which it may attack the greater articulations. It is attended with various sympathetic phenomena, particularly in the digestive organs. It may also attack internal organs, as the stomach, the intestines, etc. It is an inherited disease of purine metaboism, which causes an increased level of uric acid in the blood, and leads to deposition of crystals of sodium urate in cartilage within joints and in connective tissue. It can be alleviated by a diet low in purines, and is treated by drugs which block formation of uric acid.

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6/3/08 11:32 P

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Boy, that stinks about your gout and your personal life. Thank you for hanging in there, Sandy. I know you will be so relieved that this horrible pain is finally gone.

A big CONGRATS on the weight loss! It may not have been a fun way to lose those two pounds, but any loss is great!!!

Now to get rid of the pain! You can do this, Sandy. More prayers coming your way, and that includes your doctor, too. emoticon

Feel free to send me a private e-mail if you feel like venting or just want someone to listen without feedback. I'm always here for you.



Look into your heart, work towards your dreams, and they will come true.

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IT*SNEVER2LATE's Photo IT*SNEVER2LATE Posts: 4,026
6/2/08 4:50 P

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Janet-
I've still got the bouts...Day #10 of Prednisone- no improvement. If anything,it's worse. But I'm tough, like you said! My personal life is a different story.
I think I've actually lost a couple pounds!

Sandy emoticon

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6/2/08 1:47 P

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How is life, Sandy? You doing better? You remain in my thoughts and prayers.

I wish you were one of those people who only get one episode of gout, but I know you are tough and will do what it takes to get rid of the silly pain.

Love you!

Look into your heart, work towards your dreams, and they will come true.

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6/1/08 7:49 P

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JANET!

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6/1/08 6:09 P

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I'm not sure how I got on their mailing list, but I just got the summer issue of "Remedy" magazine. It has an article about dealing with different types of arthritis. "Joint Decisions." The section about gout is duplicative of many of Sandy's posts, but I thought it was very informative for a summary about gout:

GOUT

Once considered "the wealthy fat man's disease" because of its link to rich foods and alcohol, gout -- a buildup of monosodium urate crystals in joints and tissues--is now known to strike others as well. Those with genetic predisposition are particularly at risk. The majority of the nation's more than 2 million gout sufferers are men in their 40s and 50s, but women can get it too, especially after menopause. During an attack, one or more joints become painful, hot, swollen and purple, often accompanied by fever and chills.

Prevention

Some medications, including diuretics, low-dose aspirin and the immune suppressant cyclosporine, are known to boost risk. Your doctor should also monitor you closely if you have hypertension or diabetes, which are also linked to gout. If you've had an attack of gout or have a family history of it, avoid food and drink high in purines--the compounds that produce the uric acid that leads to the crystal formation--and boost your intake of dairy. (Organ meats, anchovies, beer, wine and gravy are the main things to avoid.) You may also want to forgo regular soda, a new report from a 12-year follow-up study found that having even five sugared soft drinks a week increase one's risk of getting gout.

Diagnosis

Other joint conditions, including rheumatoid arthritis and bacterial joint infections, may be confused with gout. To get a proper diagnosis, your doctor will draw a small amount of synovial fluid from a swollen joint, then look under the microscope for the tell-tale needle-shaped crystals.

Treatment

Acute attacks are managed with rest, nonsteroidal anti-inflammatory drugs like indomethacin (or, sometimes, the medicines prednisone or colchicine).

"For reasons we don't completely understand, about 10 percent of people who have one attack never have another," Dr. [Mary Chester] Wasko says. "So doctors typically wait until a person has had a second attack before initiating long-term preventive therapy."

Usually, at that point, urate-lowering drugs like allopurinol or probenecid are prescribed.

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5/30/08 11:08 P

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Here is some info on Alloprinol from the Medline website.

www.nlm.nih.gov/medlineplus/print/dr
ug
info/medmaster/a682673.html


Drug Information: Allopurinol
(al oh pure' i nole)


Why is this medication prescribed?
Allopurinol is used to treat gout, high levels of uric acid in the body caused by certain cancer medications, and kidney stones. Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is used to prevent gout attacks, not to treat them once they occur.

How should this medicine be used?
Allopurinol comes as a tablet to take by mouth. It is usually taken once or twice a day, preferably after a meal. To help you remember to take allopurinol, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take allopurinol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of allopurinol and gradually increase your dose, not more than once a week.

It may take several months or longer before you feel the full benefit of allopurinol. Allopurinol may increase the number of gout attacks during the first few months that you take it, although it will eventually prevent attacks. Your doctor may prescribe another medication such as colchicine to prevent gout attacks for the first few months you take allopurinol. Continue to take allopurinol even if you feel well. Do not stop taking allopurinol without talking to your doctor.

Other uses for this medicine
Allopurinol is also sometimes used to treat seizures, pain caused by pancreas disease, and certain infections. It is also sometimes used to improve survival after bypass surgery, to reduce ulcer relapses, and to prevent rejection of kidney transplants. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?
Before taking allopurinol,

- tell your doctor and pharmacist if you are allergic to allopurinol or any other medications.

- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: amoxicillin (Amoxil, Trimox); ampicillin (Polycillin, Principen); anticoagulants ('blood thinners') such as warfarin (Coumadin); cancer chemotherapy drugs such as cyclophosphamide (Cytoxan) and mercaptopurine (Purinethol); chlorpropamide (Diabinese); diuretics ('water pills'); medications that suppress the immune system such as azathioprine (Imuran) and cyclosporine (Neoral, Sandimmune); other medications for gout such as probenecid (Benemid) and sulfinpyrazone (Anturane); and tolbutamide (Orinase). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

- tell your doctor if you have or have ever had kidney or liver disease or heart failure.

- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking allopurinol, call your doctor.

- you should know that allopurinol may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
ask your doctor about the safe use of alcoholic beverages while you are taking allopurinol. Alcohol may decrease the effectiveness of allopurinol.
What special dietary instructions should I follow?
Drink at least eight glasses of water or other fluids each day while taking allopurinol unless directed to do otherwise by your doctor.

What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?
Allopurinol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

upset stomach
diarrhea
drowsiness

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

skin rash
painful urination
blood in the urine
irritation of the eyes
swelling of the lips or mouth
fever, sore throat, chills, and other signs of infection
loss of appetite
unexpected weight loss
itching

Allopurinol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to allopurinol.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):
Aloprim®
Zyloprim®

Last Revised - 07/01/2003
Last Reviewed - 08/01/2007



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5/28/08 10:46 P

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Thanks for the encouragement,Janet. I was going to do some research on Prednisone,but I got caught up on the other drugs that they use for gout. Most of them have been around for awhile,and some could use improvement. That Colchicine is worse than having a hangover!!!

He prescribed a 4-week course. The last week, I cut the dose in half. When I've been on the Prednisone for 2 weeks,I'm supposed to start Allopurinol,which is supposed to decrease the uric acid. I think I'm supposed to stay on that one all of the time. Prednisone is NOT a feel-good drug. In my case, it's supposed to be an anti-inflammatory agent. They say Gouty Arthritis is the worst kind there is.

Sandy emoticon

Edited by: IT*SNEVER2LATE at: 5/28/2008 (22:57)
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5/28/08 10:11 P

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At least the prednisone is helping a little. Are you experiencing any other side effects of it besides the high BG? I know you wish it would work faster. How long do you have to take it? Now I want to do research on prednisone so I know what you are going through. As always, you are in my thoughts and prayers, Sandy!

Look into your heart, work towards your dreams, and they will come true.

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5/28/08 8:09 P

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DAY #5- PREDNISONE

Pain slightly improved 7/10. Blood sugar 260 this afternoon,several hours after turkey sandwich. I expected high readings. Not totally on program,but at least I don't have a bunch of junk food on hand.

Sandy ):

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5/28/08 6:36 P

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This article is from the News Archive of the Gout & Uric Acid Education Society. The link is at the bottom of the article.

The site does not allow for access to the full articles, but some of this info may be helpful anyway.

PR Newswire (May 22, 2007)
Survey Reveals Lack of Knowledge about Gout – a Common Form of Painful Arthritis

Summary: Even though more than two million Americans suffer from it, 40 percent of the nation’s population does not realize gout is one of the most painful forms of arthritis, according to a recent survey sponsored by the Gout & Uric Acid Education Society. Dr. Lawrence Edwards, chairman of the Gout & Uric Acid Society, a nonprofit organization dedicated to gout education, said the Society will join with the Arthritis Foundation to promote better understanding of the disease by launching the first annual National Gout Awareness Day on May 22, 2007. Survey Reveals Lack of Knowledge

New York Times (March 12, 2007)
“Tsai-Fan Yu, 95, Physician, Dies; Helped Alleviate Gout”

Summary: Dr. Tsai-Fan Yu, a physician and researcher at Mount Sinai Medical Center who helped explain a primary cause of gout and who evaluated early drugs to treat the disease that are still in use, died on March 2 in Manhattan. She was 95. The cause was respiratory complications following a stroke.

In the 1950s, Dr. Yu helped to found a groundbreaking clinic at Mount Sinai to treat gout. Working with Dr. Alexander B. Gutman, who was a chairman of the department of medicine there, Dr. Yu helped establish a connection between elevated levels of uric acid and the pain experienced by patients with gout.

Dr. Yu, Dr. Gutman and others tested a drug, probenecid, which was shown to remove excess uric acid by causing it to be excreted in urine. Probenecid proved to be a success and remains in use today as a treatment for gout.

Dr. Yu and Dr. Gutman later conducted a five-year study of an anti-inflammatory drug, colchicine, and its effects on 208 patients, evaluating its usefulness in preventing recurring attacks of acute gout. Colchicine was also a success and remains in use.

In the 1960s, Dr. Yu, with Dr. Gutman and others, continued her pioneering studies of gout's mechanisms and evaluated allopurinol, a drug that helps interrupt the formation of uric acid and still is used in treating gout and kidney stones.

Tsai-Fan Yu was born in Shanghai. She received her medical degree from Peking Union Medical College in 1936. Dr. Yu arrived in the United States in 1947 and taught at Columbia before moving to Mount Sinai as an associate professor of internal medicine in 1957. In 1973, she became the first woman to be appointed a full professor at Mount Sinai, a position she held until retiring in 1992.

Datamonitor News and Comment (March 7, 2007)
“Savient reaches recruitment target in gout study”

Summary: Savient Pharamceuticals announced it has reached its enrollment target of 200 patients in two, phase III trials assessing the safety and efficacy of Puricase in patients with treatment-failure gout. The goal of the study is to show normalization of uric acid during the third and sixth months of the six-month trial. The study will also look for the reduction in the burden of gout tophi, fewer number of gout flares, and the reduction in the number of tender and swollen joints during the six-month time period.

“Up to this point, the tolerability of intravenous dosing has been good, with a low rate of infusion reactions across all placebo and Puricase infusions. Even more importantly, physicians appear to be highly successful in treating through infusion reactions when they do occur, just as in clinical practice with other infused biologicals,” stated Zeb Horowitz, senior vice president of Savient.

Results from the phase III trials are expected to be released by the end of the year. Savient anticipates a biologics license application filing in early 2008.

Savient Pharmaceuticals is a biopharmaceutical company engaged in developing and marketing pharmaceutical products that target unmet medical needs in both niche and broader markets.

Reuters News (October 12, 2006)
"More than 20 percent of U.S. adults have arthritis-CDC"

Summary: More than 20 percent of U.S. adults have arthritis and more than a third of them have limited activity because of it, according to the U.S. Centers for Disease Control and Prevention. The CDC looked at information in an annual survey of 30,000 people for its report, published in the agency's weekly summary of disease and death. The survey covered various forms of arthritis including rheumatoid arthritis, gout, lupus and fibromyalgia.

Fresno Bee (October 8, 2006)
"About gout; 'Disease of kings' actually affects people of all ranks"

Summary: Imagine stubbing your big toe against an iron bedpost or sticking it into a hornet's nest. That kind of intense pain may make you grind your teeth, but it's nothing compared to a gout attack. No monarch, let alone a peasant or commoner, should have to endure such agony. Yet, for centuries, gout was called the "disease of kings," and rulers such as Henry VIII, Charles V and George IV suffered attacks that often left them with feet propped up in misery. Modern-day gout sufferers can identify with the vexation depicted in illustrations from that bygone era.

AFX International News (October 2, 2006)
"Ipsen application to market anti-gout treatment wins EU validation"

Summary: French pharmaceuticals group Ipsen said the European Medicines Agency (EMEA) has validated its application to market febuxostat in the EU for the management of symptomatic hyperuricaemia, or raised uric acid in the blood. The validation signifies that the EMEA can now begin a review of Ipsen's Marketing Authorization Application (MAA).

News Index
Reuters Health E-Line (September 26, 2006)
"Alcohol may trigger gout attacks"

Summary: Drinking alcohol, even a small amount, may trigger recurrent painful bouts of gout, a study shows. The gout-triggering effect of alcohol "occurs within a short period of time, perhaps less than 24 hours," study investigator Yuqing Zhang from Boston University told Reuters Health. "Thus, subjects with established gout should avoid drinking alcohol."

NewsRx.com (September 24, 2006)
"Drug Safety; Diuretics may not increase gout risk"

Summary: According to recent research published in the journal Annals of the Rheumatic Diseases, "It is taken for granted that diuretics may induce gout, but there is a general lack of evidence on this topic." H.J. Janssens and colleagues at University Medical Center of Nijmegen aimed "to determine the incidence of gout in patients who use diuretics, taking into account concurrent hypertension and cardiovascular diseases."

Cooking Light (March 2006)
"Gout: A Royal Pain"

Summary: A diet too rich in meat and poor in low-fat dairy and vegetables may lead to join pain.

Good Housekeeping (March 2006)
"I don't remember stubbing my toe"

Summary: Donna (not her real name) had no idea why her big toe was so sore. When it became red and swollen, she hobbled off to her internist.

PRWeb (March 4, 2006)
"Cheney Suffers Complications From Gout Medication"

Summary: In January, Vice President Dick Cheney was rushed to the hospital, suffering shortness of breath, a result of fluid retention in his lungs. The fluid in his lungs was caused by anti-inflammatory prescription that Cheney was taking for gout.

www.gouteducation.org/news/news_arch
iv
e.aspx


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DAY #4- PREDNISONE

I am absolutely miserable. My foot is so swollen that the skin is stretched out. It feels like I'm walking on BIG rocks,and I can't move my toes. ENOUGH! I'm craving sweets and I'm very crabby (when I'm not crying ):) The good news is that my neck that I injured 40 yrs.ago feels great (the swelling is down), so I haven't devised a plan to kill myself (or somebody else!) yet.

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OVERVIEW- URIC ACID TEST

health.yahoo.com/arthritis-diagnosis
/u
ric-acid-in-blood/healthwise--aa1202R>3.html


SANDY

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I confidently affirm that the greater part of those who are supposed to have died of gout, have died of the medicine rather than the disease - a statement in which I am supported by observation.
~~~~~~~~~~~~~~~~~
The medicine which they speak of is undoubtedly Colchicine...I considered it worse than the pain!

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5/26/08 12:06 A

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Thanks,Janet! I read that,and it is very informative. I'm learning alot about gout,thanks to you,and all of the other information available.

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This article about Maurice Cheeks, NBA basketball player and coach, and his gout was in the SP Health News section:

www.sparkpeople.com/resource/health_
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ws_detail.asp?health_day=615806


Edited by: JANEXA at: 5/25/2008 (23:55)
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1) Uric Acid Crystals can take a long time (months or years) to accumulate, most commonly in connective tissues in and around joints, especially in the lower limbs. During this period there may well be no symptoms whatsoever. About 95% of people with hyperuricaemia (high uric acid in the blood supply) will not have a gout attack throughout their entire lives. However, they may experience pain and discomfort from crystallized uric acid in their joints. Pain in the heel, "Achilles Tendon", is very common. Sometimes uric acid problems are even misdiagnosed as Rheumatoid Arthritis. The uric acid crystals will cut into the synovial fluid sacks that cushion all joints releasing the synovial fluid into the blood. This can cause blood readings to indicate Rheumatoid Arthritis when in fact the problem is really uric acid crystals.

2) Acute attacks are where a single joint is almost always involved in all initial episodes, and most often in the joint of the big toe. Typically local irritation and aching proceeds to tissues becoming swollen, red, hot, shiny and extremely painful. The pain is often described as the worst ever experienced.

3) There are periods between attacks. Some never have a second attack, or perhaps after many years, but in most the second attack occurs within a year. The frequency, severity, and number of joints involved tend to increase over time, eventually leading into joint damage and chronic pain after an average of about 10 years.

4) Chronic tophaceous gout large crystal deposits, or tophi, produce irregular firm nodules predominantly around the upper surfaces of the fingers and hands. They can form in other places as well, including forearms, Achilles tendons, and/or the ears. When untreated, these can lead to severe deformity

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Over 70% of your immune system is in your digestive tract. Do you have enough friendly bacteria to handle this large task? About 30% of all uric acid is expelled through the bowels with the help of Friendly Bacteria,in the form of PROBIOTICS.

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JANET-
I see other people's suffering as much worse than mine. I've read that sour cherries are good for gout. I bought some organic cherry juice concentrate that I'm going to start today. The article I read said it took 30 days before it started working. I'm not eating any of the "offending" foods,except I did have shrimp a couple of times. It's my uric acid. When I went to the Dr. week before last,my uric acid was 13.9 and it's not supposed to be above 7. My kidneys are not able to process it out of my body. What really bothers me,is that it is probably making my kidneys worse. From all indications,this will be a chronic gouty arthritis.Humility is good for the soul!

I already planned on telling them at my 1st appt.that I would need a wheelchair escort to my next appt.

Thanks for caring!
Sandy

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Sandy, What in the world is your body doing to you? That is horrible--7 weeks! Does any food help it at all? Please let me know what the doctor says. You are always in my thoughts and prayers, Sandy. My little problems seem so small compared to yours, but I know it is all relative. Each person's suffering is terrible for that individual. Man! I just feel like there must be something else the doctor can suggest to get this stupid gout pain out of your life.

I wish you could borrow someone's wheelchair at the hospital. I bet they will get one for you when they hear about your gout.

You take care. I know you are doing everything you know to do to help yourself out, and please get as much rest and stay off your feet for as long as you need to. From what I've read, I guess staying off your feet helps a litte bit.


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JANET-
Thanks for the article from Mayo. I woke up with my friend again this morning. This time it's on my heal going up either side of my achilles tendon. It's hot and inflammed,but not quite as painful. Great...I have 2 appointments at the hospital...at opposite ends. I'm gonna need them to wheel me to my second appt. No way can I get over there in time. I hope I can sleep tonight. My heel is throbbing and burning. I'm bloody well sick of this! I counted on the calendar,and I've had this for 7 weeks,and this is my 3rd attack. Would that put me in the chronic category. Colchicine is the only thing I can take and it makes me nauseous and gives me diarrhea...just when it was gone! I have some Allpurinal,but you're not supposed to take that until the gout episode is TOTALLY gone,which is has never been. That's my saga. If I asked to see Rheumatology Thrusday, I can just hear them laughing! Talk soon, Sandy

Edited by: IT*SNEVER2LATE at: 5/21/2008 (00:38)
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This is from the Mayo Clinic's site, and they have a pretty comprehensive set of articles related to gout. Most of this you already know from experience or the research you (Sandy) have included for the team. Here is the link to the introduction page: you
can access the rest of the mini-articles through this introduction page.
www.mayoclinic.com/health/gout/DS000
90
/DSECTION=1


I will copy and paste the two mini-articles about nutrition/diet (and the links) to our "Nutrition and Gout" thread, so it will be easier for you and the rest of the team to refer to it.
Signs and symptoms

The signs and symptoms of gout are almost always acute, occurring suddenly — often at night — and without warning. They include:

Intense joint pain. Gout usually affects the large joint of your big toe but it can occur in your feet, ankles, knees, hands and wrists. If untreated, the pain typically lasts five to 10 days and then stops. The discomfort subsides gradually over one to two weeks, leaving the joint apparently normal and pain-free.

-Inflammation and redness. The affected joint or joints become swollen, tender and red.

Causes

Gout occurs when urate crystals accumulate around your joint, causing the inflammation and intense pain of a gout attack. Urate crystals can form when you have high levels of uric acid in your blood. Your body produces uric acid when it breaks down purines, substances that are found naturally in your body, as well as in certain foods, such as organ meats, anchovies, herring, asparagus and mushrooms.

Normally, uric acid dissolves in your blood and passes through your kidneys into your urine. But sometimes your body either produces too much uric acid or your kidneys excrete too little uric acid. When this happens, uric acid can build up, forming sharp, needle-like urate crystals in a joint or surrounding tissue that cause pain, inflammation and swelling.

Risk factors

You're more likely to develop gout if you have high levels of uric acid in your body. Factors that increase the uric acid level in your body include:

- Lifestyle factors. Choices you make in your everyday life may increase your risk of gout.

- Excessive alcohol use — generally more than two drinks a day for men and more than one for women — increases the risk of gout.

- Medical conditions. Certain diseases and conditions make it more likely that you'll develop gout. These include untreated high blood pressure (hypertension) and chronic conditions, such as diabetes, high levels of fat and cholesterol in the blood (hyperlipidemia), and narrowing of the arteries (arteriosclerosis).

- Certain medications. The use of thiazide diuretics — commonly used to treat hypertension — and low-dose aspirin also can increase uric acid levels. So can the use of anti-rejection drugs prescribed for people who have undergone an organ transplant.

- Family history of gout. If other members of your family have had gout, you're more likely to develop the disease.

- Age and sex. Gout occurs more often in men than it does in women, primarily because women tend to have lower uric acid levels than men do. After menopause, however, women's uric acid levels approach those of men. Men also are more likely to develop gout earlier — usually between the ages of 40 and 50 — whereas women generally develop signs and symptoms after menopause.

When to seek medical advice

If you experience sudden, intense pain in a joint, call your doctor. Gout that goes untreated can lead to worsening pain and joint damage.

Seek medical care immediately if you have a fever and a joint is hot and inflamed, which can be a sign of infection.

Screening and diagnosis

Tests to help diagnose gout may include:

- Joint fluid test. Your doctor may use a needle to draw fluid from your affected joint. When examined under the microscope, your joint fluid may reveal urate crystals.

- Blood test. Your doctor may recommend a blood test to measure the uric acid level in your blood. Blood test results can be misleading, though. Some people have high uric acid levels, but never experience gout. And some people have signs and symptoms of gout, but don't have unusual levels of uric acid in their blood.

Complications
People with gout can develop more-severe conditions, such as:

- Recurrent gout. Some people may never experience gout signs and symptoms again. But others may experience gout several times each year. Medications may help prevent gout attacks in people with recurrent gout.

- Advanced gout. Untreated gout may cause deposits of urate crystals to form under the skin in nodules called tophi (TOE-fi). Tophi usually aren't painful, but they can become swollen and tender during gout attacks.

- Kidney stones. Urate crystals may collect in the urinary tract of people with gout, causing kidney stones. Medications can help reduce the risk of kidney stones.

Treatment

Treatment for gout usually involves medications. What medications you and your doctor choose will be based on your current health and your own preferences. Medications for gout include:

- Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs may control inflammation and pain in people with gout. NSAIDs include over-the-counter options such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, others), as well as more powerful prescription NSAIDs. NSAIDs carry risks of stomach pain, bleeding and ulcers.

- Colchicine. Colchicine controls gout effectively, but may cause uncomfortable side effects, such as nausea, vomiting and diarrhea. If you're unable to take NSAIDs, your doctor may recommend colchicine.

- Steroids. Steroid medications, such as the drug prednisone may control gout inflammation and pain. Steroids may be administered in pill form, or they can be injected into your joint. Side effects of steroids may include thinning bones, poor wound healing and a decreased ability to fight infection. Steroids may be reserved for people who can't take either NSAIDs or colchicine.

Prevention

Medications

If you experience several gout attacks each year or if your gout attacks are less frequent but particularly painful, your doctor may recommend medication to reduce your risk of future gout attacks. You usually begin taking preventive medications once your acute gout attack has subsided. Options include:

- Medication that blocks uric acid production. Allopurinol (Zyloprim, Aloprim) limits the amount of uric acid your body makes. This may lower your blood's uric acid level and reduce your risk of gout. Side effects include a rash and low blood counts.

- Medication that improves uric acid removal. Probenecid improves your kidneys' ability to remove uric acid from your body. This may lower your uric acid levels and reduce your risk of gout, but the level of uric acid in your urine is increased. Side effects include a rash, stomach pain and kidney stones.

Gout diet

No specific dietary changes are proved to reduce your risk of gout. However, it may make sense to eat foods that contain fewer purines. If you want to try a gout diet, try to:

- Cut back on the amount of red meat and seafood you eat.

- Avoid alcoholic beverages.

- Eat more low-fat dairy products.

- Eat more complex carbohydrates, such as whole-grain breads.

- Choose portions that allow you to maintain a healthy weight. Losing weight may decrease uric acid levels in your body. But avoid fasting or rapid weight loss, since doing so may temporarily raise uric acid levels.


Self-care

Take care of your body during a gout attack. While you're waiting for your medications to take effect, you may find it easier to cope with pain and inflammation if you:

- Reduce the amount of animal protein you eat. Government guidelines advise eating no more than 5 to 6 ounces of lean meat, poultry or fish a day for nearly everyone — especially people who have gout, because high-protein foods increase the blood level of uric acid. Organ meats (liver, brains, kidney and sweetbreads), anchovies, herring and mackerel are particularly high in purines.

- Avoid alcohol. Alcohol can inhibit the excretion of uric acid. If you're having a gout attack, it's best to avoid alcohol completely.
Drink plenty of liquids. Fluids help dilute uric acid in your blood and urine, so be sure you get enough water and other fluids every day.

Complementary and alternative medicine

If gout treatments aren't working as well as you'd hoped, you may be interested in trying complementary and alternative treatments for your gout. Discuss these treatments with your doctor first. Your doctor can help you weigh the benefits and risks and tell you if the treatments will interfere with your gout medications.

Though you may be reluctant to discuss complementary and alternative medicine with your doctor, many mainstream doctors are becoming more open to discussing these options. But, since few of these treatments have been extensively studied in clinical trials, it's difficult to assess whether these treatments are helpful for gout pain. In some cases, the risks of these treatments aren't known.

Some complementary and alternative treatments that have been studied include:

- Coffee. Studies have found an association between coffee drinking — both regular and decaffeinated — and lower uric acid levels, though no study has proved how or why coffee may have an influence on uric acid in your body. The available evidence isn't enough to encourage noncoffee drinkers to start, but it may give researchers clues to new ways of treating gout in the future.

- Vitamin C. Supplements containing vitamin C may reduce the levels of uric acid in your blood. However, vitamin C hasn't been studied as a treatment for gout. Don't assume that if a little vitamin C is good for you, then lots is better. Megadoses of vitamin C may increase your body's uric acid levels. Talk to your doctor about what a reasonable dose of vitamin C may be. And don't forget that you can increase your vitamin C intake by eating more fruits and vegetables, especially oranges.

- Cherries. Cherries have been associated with lower levels of uric acid in studies, but it isn't clear if they have any effect on gout signs and symptoms. Adding cherries and other dark-colored fruits, such as blackberries, blueberries, purple grapes and raspberries, to your diet may be a safe way to supplement your gout treatment, but discuss it with your doctor first.

Other complementary and alternative medicine treatments may help you cope until your gout pain subsides or your medications take effect. For instance, relaxation techniques, such as deep-breathing exercises and meditation, may help take your mind off your pain.

Hope both of you are doing better!

I love you both!



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Gout and Gout resources - on Medscape

Gout & Aspirin
Medical Author: William C. Shiel Jr., MD, FACP, FACR

Did you know that aspirin can affect Gout?

Many patients will read that aspirin increases the level of uric acid in the blood and that the blood level of uric acid is important in Gout. What is the relationship between the two factors? Additionally, many patients are prescribed a low dose of aspirin (75-81 mg daily) to prevent heart attacks or strokes. What should patients be told about aspirin and Gout? Will it cause Gout in them?

These questions bring up a number of important issues about Gout.

First, Gout is medical condition that is characterized by abnormally elevated levels of uric acid in the blood, recurring attacks of joint inflammation (arthritis), deposits of hard lumps of uric acid in and around the joints, and decreased kidney function and kidney stones. While Gout is often associated with an abnormally elevated blood uric acid level, it need not be. This means that the medical condition of Gout can exist in an individual regardless of an elevated uric acid level in that person. This even holds true for an acute attack of gouty arthritis! Moreover, many patients with elevated blood levels of uric acid (hyperuricemia) never develop gout.

It is, therefore, important to understand that it may not necessarily be the level of uric acid that triggers an acute attack of gout. Frequently, acute attacks are precipitated by a rapid change of uric acid, either up or down. Additionally, the tendency towards developing gout seems to be significantly influenced by the metabolism a person inherits.

Find out whether aspirin can cause a gout attack »

Top Searched Gout Terms:
diet, treatments, colchicine, alcohol, purines, causes, exercise, medication, tophi, attacks, foods that cause gout, toe, history, long-term effects, pseudogout, symptom


What is gout and hyperuricemia?

Gout is condition that results from crystals of uric acid depositing in tissues of the body. Gout is characterized by an overload of uric acid in the body and recurring attacks of joint inflammation (arthritis). Chronic gout can lead to deposits of hard lumps of uric acid in and around the joints, decreased kidney function, and kidney stones.

Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines, that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of painful arthritis (gout attack), kidney stones, and blockage of the kidney filtering tubules with uric acid crystals, leading to kidney failure. On the other hand, some patients may only develop elevated blood uric acid levels (hyperuricemia) without having arthritis or kidney problems. The term "gout" commonly is used to refer to the painful arthritis attacks.

Gouty arthritis is usually an extremely painful attack with a rapid onset of joint inflammation. The joint inflammation is precipitated by deposits of uric acid crystals in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals and release chemicals of inflammation, causing pain, heat, and redness of the joint tissues.


Who is affected by gout?

Approximately one million people in the United States suffer from attacks of gout. (Did you know that none other than Benjamin Franklin had terrible gouty arthritis!) Gout is nine times more common in men than in women. It predominantly attacks males after puberty, with a peak age of 75. In women, gout attacks usually occur after menopause.

While an elevated blood level of uric acid (hyperuricemia) may indicate an increased risk of gout, the relationship between hyperuricemia and gout is unclear. Many patients with hyperuricemia do not develop gout, while some patients with repeated gout attacks have normal or low blood uric acid levels. Among the male population in the United States, approximately ten percent have hyperuricemia. However, only a small portion of those with hyperuricemia will actually develop gout


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See also: Chronic gouty arthritis

Alternative Names
Gouty arthritis - acute; Gout - acute
Causes
Gout is caused by an overproduction of uric acid or a reduced ability of the kidney to get rid of uric acid. The exact cause is unknown. It is more common in males, postmenopausal women, and people who drink alcohol.

The condition may also develop in people with:

Diabetes
Kidney disease
Obesity
Sickle cell anemia
The condition may occur after taking medicines that interfere with uric acid excretion.

Gout has 4 stages:

Asymptomatic
Acute
Intercritical
Chronic
This article discusses acute gouty arthritis only.

Symptoms
Symptoms develop suddenly and usually involve only one or a few joints. The big toe, knee, or ankle joints are most often affected.

The pain frequently starts during the night and is often described as throbbing, crushing, or excruciating. The joint appears infected with signs of warmth, redness, and tenderness.

The attacks of painful joints may go away in several days, but may return from time to time. Additional attacks usually last long. Some people may progress to chronic gouty arthritis, while others may have no further attacks.

Specific symptoms include:

Fever (sometimes)
Joint pain
Joint swelling of the affected joints
Join stiffness
Joint redness
Skin lump which may drain chalky material

Exams and Tests
Tests that may be done include:

Blood differential
Joint x-rays (may be normal)
Synovial biopsy
Synovial fluid analysis (shows uric acid crystals)
Uric acid- blood
Uric acid - urine

Treatment
A prescription medicine called colchicine helps reduce pain, swelling, and inflammation associated with acute gout attacks. The medication decreases the inflammation caused by uric acid crystals within the joint. It does not decrease the uric acid levels in the bloodstream.

The pain often goes away within 12 hours of starting treatment, and is completely relieved in 48 hours. Daily use of colchicine or allopurinol helps prevent future attacks.

Your doctor may also recommend that you take non-steroidal anti-inflammatory drugs (NSAIDs) as soon as symptoms start to relieve pain and inflammation. Strong painkillers such as codeine may occasionally be prescribed.

Corticosteroids can also be very effective. Your doctor may inject the inflamed joint with steroids to relieve the pain.

Drinking more fluids helps prevents the formation of kidney stones.

Sometimes, a diet low in purines is prescribed. Organ meats, beer, wine, and certain types of fish contain high levels of purines.



Outlook (Prognosis)
Proper treatment of acute attacks allows people to live a normal life. However, the acute form of the disease may progress to chronic gout.

Possible Complications
Side effects of medications
Chronic gouty arthritis
Kidney stones
Kidney dysfunction

When to Contact a Medical Professional
Call for an appointment with your health care provider if you have symptoms of acute gouty arthritis.

Prevention
The disorder itself may not be preventable, but you may be avoid to avoid things that trigger your symptoms. Limit alcohol consumption and follow a low-purine diet.


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I subscribe to Bayer Health newsletter because Bayer is the parent company who makes my diabetes meter, Breeze2.

The following link talks about osteoarthritis and diabetes, and although I don't know if gout is a form of osteoarthritis, I thought there might be something useful to know in this article.

www.bayereasycare.com/2008-Newslette
rs
/May-2008-eNewsletter/(Osteo)ArthritR>is-and-Diabetes-.aspx


I am going to read it now, so I apologize if this has nothing to do with gout....



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You are very welcome, Sandy. I put it in my faves, too.

Look into your heart, work towards your dreams, and they will come true.

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Janet-

For the informative article. I have never heard of familydoctor.org, but I will put it in my faves.

Sandy emoticon

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I started some research today, and this came from familydoctor.org. I learned a lot from this article, and know that I will learn a lot more as I do more research. I could be at risk for gout if I'm not careful because I love salmon and am still overweight. More of a reason why I want to do research--so I can avoid getting it, and to help my friends.

Gout

What is gout?

Gout is a kind of arthritis caused by too much uric acid in the joints. Uric acid is a substance that forms when your body breaks down a substance called purines. This substance normally dissolves in your blood and passes through your kidneys into your urine. In people with gout, uric acid builds up and forms sharp crystals that can collect around the joints. This causes pain and swelling in the affected joints.

Who can get gout?

If you eat a lot of foods that are rich in purines, you may get gout. Some of these foods are salmon, sardines, liver and herring.

You may get gout if you’re overweight, drink alcohol or have high cholesterol. Men have gout more often than women do. Women are more likely to have gout after menopause.

Medicines that may cause gout include the following:

certain diuretics (“water pills”)
niacin (a B-complex vitamin)
aspirin (taken in low doses)
cyclosporine (brand names: Sandimmune, Neoral, SangCya)
some drugs used to treat cancer

What is a gout attack like?

It may be sudden. It usually starts at night, often in the big toe joint. The affected joint becomes red, feels hot and hurts. The joint hurts more when you touch it. Other joints may also be affected.

What should I do if I have a gout attack?

You should rest in bed. Putting a hot pad or an ice pack on the joint may ease the pain. Keeping the weight of clothes or bedding off the joint can also help. Medicines that you can take without a prescription that reduce inflammation, such as aspirin or ibuprofen (one brand name: Motrin), may help. Your doctor can also prescribe medicine for you.

The sooner you get treatment, the sooner the pain will go away. Your doctor can prescribe medicine to stop the joint swelling and pain. With treatment, your gout attack should go away in a few days.

What if I don’t get treatment?

If you don’t get treatment, a gout attack can last for days or even weeks. If you keep having more attacks, more joints will be affected, and the attacks will last longer.

If you have gout attacks for many years, you may develop tophi (say “toe-fee”). These are soft tissue swellings caused by uric acid crystals. Tophi usually form on the toes, fingers, hands and elbows.
You may also get kidney disease or kidney stones. Over time, the bone around a joint may be destroyed by gout.

What can I do to avoid gout attacks?

Your doctor can prescribe medicines to prevent future gout attacks. These medicines can wash the uric acid from your joints, reduce swelling and keep uric acid from forming.

Lose weight if you are overweight. If you have high blood pressure or high cholesterol, get treatment and follow a low-salt, low-fat diet.

Stay away from alcohol and foods that are high in purines. Drink lots of water. It can help flush uric acid from your body.

Source
Written by familydoctor.org editorial staff.

Diagnosis and Management of Gout by JR Pittman, Pharm.D. and MH Bross, M.D. (American Family Physician April 1, 1999, http://www.aafp.org/afp/990401ap/1799.html
)

Reviewed/Updated: 05/06
Created: 09/00



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One of my concerns when I was diagnosed with gout was the low dose aspirin that I took every day as a prophylactic to stroke and heart attack. Looks like the low dose are safe,but I'm still asking my new Doc when I have my appt next week.

www.medicinenet.com/script/main/art.
as
p?articlekey=14814


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MEDICATIONS USED TO TREAT GOUT-

Except for decreasing the amount of alcohol intake and cutting back on meats, there is little an individual can do to avoid a gout attack. Certain medications can be used to help prevent attacks. Most of the time, gout occurs unexpectedly and has to be treated with medications.


Acute Gout: The goal of therapy for acute gout is to decrease the excruciating pain and inflammation of the joints. The medications used include:

Non-steroidal Anti-Inflammatory Drugs (NSAIDs) such as indomethacin (Indocin), ketoprofen (Orudis), oxaprozin (Daypro), diclofenac (Voltaren), ibuprofen (Motrin), etodolac (Lodine), naproxen (Naprelan), sulindac (Clinoril) and others. Non-steroidal anti-inflammatory drugs (NSAIDs) are considered to be the best treatment available, which means that they are preferred over any other medication in acute gout. NSAIDs block prostaglandins, the substance that dilates blood vessels and causes inflammation and pain of gout. NSAIDs are taken by mouth three or four times daily, usually for as long as patient has symptoms.

Colchicine has been used to treat gout for years. Colchicine works well to eliminate the pain of gout; however, many patients cannot tolerate its side effects, which include diarrhea, nausea, vomiting, and abdominal cramps. For this reason, colchicine is regarded as a second line therapy for acute gout and is only used in patients with a contraindication to NSAIDs.

Corticosteroids, such as prednisone, prednisolone, and triamcinolone. Some steroids can be injected directly into the joint or a muscle to relieve the pain locally. Steroids are not used very often in acute gout because they do not work as well as NSAIDs or colchicine. They are the "last resort" therapy, used only in patients that cannot take NSAIDs or colchicine (as determined by a physician).

Chronic Gout: The goal of therapy for chronic gout is to prevent an acute gout attack from recurring. This is sometimes accomplished by decreasing the uric acid levels. The following medications are used:

Xanthine Oxidase Inhibitors, such as allopurinol work by decreasing the amount of uric acid produced by the body. Allopurinol is usually prescribed for patients who produce excessive amounts of uric acid in their body ("overproducers").

Uricosuric Agents, such as probenecid or sulfinpyrazone, work by helping the kidneys get rid of the excess uric acid produced in the body. Uricosuric agents are usually prescribed for patients whose kidneys cannot eliminate uric acid from the body ("underexcreters").

Edited by: IT*SNEVER2LATE at: 4/29/2008 (16:01)
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Info from articles,Webmd.com,research,natural cures,dietary tips,anything on the subject of gout.

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