Normal human physiology is not designed for frequent small meals and remains essentially unchanged from that of our prehistoric ancestors. Neanderthal man was more accustomed to starvation and long gaps between meals than tucking into limitless dinosaur snacks by the fire. As such, humans are hardwired to be hungry and to store food away as fat. The two major hormones, insulin and leptin work together to manage fat stores. After a meal insulin rises for three hours, initially replacing glycogen stores and then shunting any extra calories into fat. As insulin levels fall we become able to access our fat stores as a source of energy. Eating another meal or snack at this point causes a further release of insulin, which not only inhibits our ability to burn fat but also acts as a strain on the pancreas. This secondary rise in insulin is more prolonged and when the cycle is repeated will eventually lead to hyperinsulinaemia and insulin resistance, forerunners of metabolic syndrome. In addition, this pattern leads to leptin resistance resulting in food cravings and a slower metabolism.
I'm down 12 pounds by simply not spreading my calories out over 5-6 small meals. (three weeks) I've been counting calories for years. And, when I looked back over my time line (using Spark tools) I found that I started to regain my weight when I started eating these 5-6 meals per day as recommended by most health "experts". It almost ruined my body.
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