Not judging anyone using HCG.....But this information may be worth looking into.
An unfortunate resurgence of human chorionic gonadotropin use for weight loss, JC Lovejoy and M Sasagawa, International Journal of Obesity, 36: 385-386
“Some 55 years ago, English physician ATW Simeons proposed to treat obesity by administering human chorionic gonadotropin (HCG). Simeons’ protocol involves a combination of up to 6 weeks of daily low-dose HCG injections and a very low calorie diet (500 kcal per day). In recent decades, several randomized controlled trials demonstrated that HCG was no better than placebo and experts concluded that HCG has no merit for weight loss. Thus the use of HCG for weight loss is discouraged by legitimate clinicians who treat obese patients.
However, since the publication of a 2007 popular book, and most recently the promotion of HCG for weight loss on the Dr. Oz television show, some conventional and many alternative medicine clinics have been offering HCG weight loss programs because it is a lucrative business for a prevalent health issue, obesity.
Anecdotal stories indicate that many patients are satisfied with these programs because of the success of weight loss, although any weight loss that occurs is very likely due to the hypocaloric diet that accompanies the injections rather than any effect of HCG per se and; as there is usually no maintenance program provided, weight is quickly regained after the end of the program.
In addition to its lack of efficacy, it is concerning that the HCG dosage administered to obese patients is sufficiently high to cause certain physiological responses and the quality of the HCG used by many “obesity clinics” is unknown. A typical dosage used for weight loss programs is the daily dosage of 150 US for six times per week or a weekly dosage of 1000IU. In a clinical trial of oocyte production, a daily dose of 200IU has been successfully used for maintaining late follicular phase as a gonadotropin-releasing hormone antagonist.
The likelihood that HCG administered for weight loss is having reproductive effects is further suggested by the finding of luteinizing hormone/HCG receptors on various tissues. Preliminary studies showed that HCG facilitated decidualization of stromal cells of human endometrium, which raises concern of possible leimyoma formation and exacerbation of endometriosis.
For males, animal prostate cells expressed HCG receptor gene upon stimulation, and the authors concluded that luteinizing hormone/HCG receptors are linked to the development of prostatic hyperplasia and prostate carcinomas.
Carlson et al, report that luteinizing hormone/HCG receptor mRNA was found from autopsy archival samples of benign gynecomastica and male breast carcinoma, and suggested that luteinizing hormone and HCG might have a role in the pathogenesis of male breast disorders at sufficiently high dosage.
Given that HCG has no demonstrated weight loss effects and has potential safety concerns, it is incumbent upon the scientific and clinical community in the obesity field to educate their patients about the lack of efficacy and potential risk of off -label HCG use and to speak out strongly against its use.”
Edited by: BECCAAPPLE at: 5/10/2013 (13:53)
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