Definitely stick away from cotton socks - either wool, or wicking socks work much better.
With blisters, prevention is definitely better than cure. Tape any hotspots as soon as they appear - that way the shoe rubs against the tape rather than your skin. Use medical tape rather than a band-aid - it sticks much better to sweaty feet.
If you must walk on an existing blister, drain it with a sterilized needle (just pass it briefly through a flame) to relieve the pressure, and treat with antiseptic to prevent infection, then tape over the top.
M@L (regular hiker and backpacker)
The reasonable man adapts himself to the world; the unreasonable one persists in trying to adapt the world to himself. Therefore all progress depends on the unreasonable man.
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