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Elevated Liver levels?

Monday, April 29, 2013

Anybody know anything about Elevated liver levels?

Not much time so I will get to the point. emoticon

Utah, my 28 month old golden retriever has epilepsy.

emoticon He is on a large dose of Zonisamide and Phenobarbitol to control his seizures.

emoticon GREAT news is that tomorrow will be 6 weeks since his last seizure. That is HUGE. Since September 2012 he has not gone over 5 weeks without a seizure.

emoticon for this.

emoticon His liver enzyme levels are high.

emoticon ATL = 606 - Normal (8.2 to 100)
Rises quickly after liver problems begin
emoticon AST = 77 - Normal (5 to 55)
Less liver specific test
emoticon ALKP = 224 - Normal (10.6 to 101)
another site shows (23 to 212)
emoticon Bilirubin = .2 - Normal (.1 to .6)

His Phenobarbitol levels are high as well. We are VERY gradually lowering the dosage. He will get more blood work done on May 16th.

The only thing I have found on the internet so far is about Mike Thistle. It shows as helping with high liver levels in people and dogs I think.

He is already on dog food with no preservatives and such... BLUE Wilderness. And His treats are no preservatives either. He usually gets carrots and now green beans as treats.

Any thoughts, input you might have is greatly appreciated.

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Member Comments About This Blog Post
    I can't help with that since I know nothing about this, but know that I'm keeping Utah in my prayers that everything is okay.

    1608 days ago
  • APED7969
    High phenobarb levels cause elevated liver enzymes. They often improve when the dose is reduced. Hopefully you can reduce the dose without having more seizures which will allow the liver to recover. Thankfully the liver is an organ with a good ability to recover from damage. I am not a big believer in supplements to improve liver function but if you choose to use them make sure you run them past your vet. Also there are specifically developed prescription diets for liver disease, Hill's l/d is one, might be worth asking about. Good luck in reducing the dose!
    1608 days ago
    Praying for you and Utah. Sorry I can't help more on this...
    Asking God to bless you both.
    Blessings and hugs,
    1609 days ago
    Wish I could help. The only thing I know about livers is that they have something to do with processing alcohol so just make sure Utah keeps his drinking to a minimum! emoticon emoticon
    1609 days ago
    Hubs suggested asking your vet about the amount of protein he's getting. Blue Wilderness is 33 plus % protein, so that may need to be looked at. High protein diets aren't recommended when you are having liver issues.
    Aire (dale) hugs to Utah!
    1609 days ago
    I wish I could help but I really know nothing about this type of stuff. Keeping it in prayer though.
    1609 days ago
    I would think that his body is not really tolerating one of his drugs well...most likely the phenobarbitol. Keep his diet steady and have everything retested when his pheno level drops a little. Hang in there. Fur babies are special "people". emoticon
    1609 days ago
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