Friday, January 04, 2013
Nearly all patients with Kidney Disease must be very familiar with creatinine level in blood test. Creatinine is the end product of muscle. Therefore, the creatinine levels may vary slightly with the muscle mass. Healthy kidneys can filter blood normally thus discharging creatinine out of blood. Consequently, the creatinine level can keep a stale level in blood. Some people may find their creatinine level may be beyond the normal level on their blood test? What does it mean?
In normal cases, our kidneys can filter our blood so as to keep the substances that body needs in blood as well as discharge the metabolic wastes. That is to say creatinine level is closely related to glomerular filtration rate (GFR). The lower GFR is, the higher the creatinine level will be. When the nephrons are extensively destroyed or impaired, the creatinine level will rise. In fact, creatinine level is not a very sensitive index in reflecting renal function. The creatinine level will rise until more than half of kidneys are necrotic or damaged. If the creatinine level is three times as high as the reference level, it means that more than 75% of the kidney function has been lost. The reference levels of creatinine level are as follows:
Male: 0.6~1.2 mg/dl
Female: 0.5~1.0 mg/dl
Infants: 0.2 mg/dl or higher
Person with one kidney: 1.8~1.9 mg/dl
In some countries, they express creatinine level in ¦̀mol/L as units. 1 mg/dl approximately amounts to 88.4 umol/l. Moreover, the reference level of creatinine may vary slightly with different countries and even different labs.
After the above analysis of the causes of higher creatinine level, you should be careful if it is above the normal level and go for further checks to find the root cause. If the diet influence, trauma, intense exercise are excluded, the possibility of kidney disease is very high. If so, you should receive relative treatment to stop its further progression of kidney disease. The earlier treatment you receive, the better prognosis you will get.