"Many synthetic vitamins lack the transporters and co-factors associated with naturally-occurring vitamins because they have been “isolated.” The Organic Consumers Association emphasizes that isolated vitamins cannot be used or recognized by the body in the same way as the natural version."
I try to use supplements that are derived from natural source,
I think over all supplements have benefited my life with reducing anxiety, and helping with other ailments, and on the balance, have not directly contributed to my weight gain.
Now , since my anxiety is hugely reduced to, then maybe for me, I burn off less cals.
this is how I feel, and we are all unique, and react in different ways