I bought some minimalist Dr. Scholl's running shoes (they look like old-fashioned sneakers). I had been reading about barefoot running, and these were on the clearance shelf at DSW. I had a gift card, so I decided to try them. So far, I love them.
Running more on your toes really works the calves. The info I've read says to start out with short runs and build up distance. I was so excited about trying them out that I went for an hour run the first time. My calves were really tight for days!
I don't know that I'd go for the Vibram, but I do like the shoes that I bought. I'm a natural forefoot runner anyway. It's not been too much of an adjustment for me.
I did wear socks. I'm not sure about socks w/Vibrams. Those toe socks that were in fashion when I was a kid were hot. I can't imagine running in them.