It really depends on how big of a meal you had and the intensity level you are going to be working out at. If it's a full meal, 1-2 hours is a good time to wait. If you are having cramps at about an hour after eating, you may want to try waiting 1.5 - 2 hours after you eat before you do your treadmill workout to see if that makes a difference for you. It may take some experimenting to see what works best for you and your body.
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