Are New FDA-Approved Diet Drugs Worth the Risk?
Within the past month, the FDA has approved two new prescription weight-loss drugs. While neither drug is being touted as a “magic pill” that will make weight loss a quick and easy process, they are still marketed as an aid to help those with significant weight loss goals. It’s important to understand what these drugs do and how they work so that you can make informed decisions when it comes to your health.
Qysmia, which was approved in July, is a combination of two older drugs: phentermine (an appetite suppressant) and topiramate (which enhances feelings of satiety after eating.) Beliviq, a similar drug the FDA approved in June, works by activating receptors in the brain that make a person feel full. Both drugs are approved for two types of people: obese individuals, and those who are overweight with at least one other health condition such as high blood pressure or type 2 diabetes. It is recommended that both drugs be used in combination with a healthy diet and regular exercise to promote weight loss.
Both drugs carry significant risks. Qysmia’s side effects can include (but are not limited to) heart palpitations and risk to a pregnant woman’s unborn baby. Belviq’s side effects can include (but are not limited to) problems with attention and memory. Because of the risks, Qysmia can only be dispensed by specially certified drugstores.
“In late-stage clinical trials, patients on the middle dose of Qsymia lost an average of 8.4 percent of their weight after one year. Those on the high dose lost 10.6 percent. By comparison, those on Arena’s Belviq lost an average of 5.8 percent of their weight after one year.” Although the average rate of weight loss was smaller with Belviq, the risks associated with this drug appear to be lower. The price of these drugs is yet to be revealed, but they aren’t expected to be cheap and won’t be covered by many insurance providers.
It’s been 13 years since the FDA last approved a prescription weight-loss medication. Until now, only one drug (Xenical) had been approved for long-term use and it was not commonly prescribed. (If you’re wondering about Alli, that’s an over-the-counter drug that anyone can purchase.) The FDA has hesitated giving approval to diet drugs in recent years, given the history of safety issues with products like fen-phen.
I can understand why these drugs are tempting to try. Weight loss can be a slow and difficult process, especially when you’re working hard and not seeing the results you’d expect. Who wouldn’t want an extra boost to lose weight more quickly and easily? But in my opinion, it’s better to look at the bigger picture. Sure, you might see a slightly lower number on the scale than you would have through diet and exercise alone. But is it worth the risk? Isn’t it best to lose weight in a healthy way by establishing habits you can stick with for the rest of your life? That way you’ll keep the weight off for good and not expose yourself to unnecessary danger just to lose a few extra pounds. That’s my 2-cents.
What do you think?
Qysmia, which was approved in July, is a combination of two older drugs: phentermine (an appetite suppressant) and topiramate (which enhances feelings of satiety after eating.) Beliviq, a similar drug the FDA approved in June, works by activating receptors in the brain that make a person feel full. Both drugs are approved for two types of people: obese individuals, and those who are overweight with at least one other health condition such as high blood pressure or type 2 diabetes. It is recommended that both drugs be used in combination with a healthy diet and regular exercise to promote weight loss.
Both drugs carry significant risks. Qysmia’s side effects can include (but are not limited to) heart palpitations and risk to a pregnant woman’s unborn baby. Belviq’s side effects can include (but are not limited to) problems with attention and memory. Because of the risks, Qysmia can only be dispensed by specially certified drugstores.
“In late-stage clinical trials, patients on the middle dose of Qsymia lost an average of 8.4 percent of their weight after one year. Those on the high dose lost 10.6 percent. By comparison, those on Arena’s Belviq lost an average of 5.8 percent of their weight after one year.” Although the average rate of weight loss was smaller with Belviq, the risks associated with this drug appear to be lower. The price of these drugs is yet to be revealed, but they aren’t expected to be cheap and won’t be covered by many insurance providers.
It’s been 13 years since the FDA last approved a prescription weight-loss medication. Until now, only one drug (Xenical) had been approved for long-term use and it was not commonly prescribed. (If you’re wondering about Alli, that’s an over-the-counter drug that anyone can purchase.) The FDA has hesitated giving approval to diet drugs in recent years, given the history of safety issues with products like fen-phen.
I can understand why these drugs are tempting to try. Weight loss can be a slow and difficult process, especially when you’re working hard and not seeing the results you’d expect. Who wouldn’t want an extra boost to lose weight more quickly and easily? But in my opinion, it’s better to look at the bigger picture. Sure, you might see a slightly lower number on the scale than you would have through diet and exercise alone. But is it worth the risk? Isn’t it best to lose weight in a healthy way by establishing habits you can stick with for the rest of your life? That way you’ll keep the weight off for good and not expose yourself to unnecessary danger just to lose a few extra pounds. That’s my 2-cents.
What do you think?
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Comments
- 8/9/2012 9:36:34 AM
And guess who had heart surgery several years later?? Yup -- ME! It was directly attributed to that medication. THOUSANDS of us had to have our aortic valves replaced! And the pharmaceutical company had to pay out, as they were found to be at fault.
I would NEVER take diet meds again -- NEVER!
Meds will never fix the issues behind the eating; that's up to me (with the help of a therapist if need be.. which I am doing).
Ok, off my soapbox. :)
Debb - 8/8/2012 5:22:52 AM
That said, weight loss is NOT in a pill, it's much more involved and lifestyle trumps all else.
As a physician, I have in the past prescribed weight loss drugs for patients, because the individual needs help. This was before SparkPeople, but WW and other weight loss programs were available (and I strongly recommended them for education, support, and accountability).
One problem that will occur is people will get these medications and give them to friends or sell them. Sad, but true. There will be lots of young girls in particular who will take them in an effort to "be skinny." They will use them without prescriptions, supervision, or medical indication.
And there WILL be complications - it's inevitable.
People will go to their doctor and DEMAND a prescription, whether they meet the criteria or not. If they are refused, they will doctor shop until they get the prescription somewhere else.
Hopefully people will not be handed a pill by itself, but given a complete personalized plan to help them reduce their health risks and improve their lives.
I hope people do not waste a lot of money on these medicines, and that few lives are lost from complications. - 8/8/2012 12:38:21 AM
Plus in taking his advice I have lost 7 kilos in the last handful of weeks.
I have always been a dedicated gym goer and eat exceptionally carefully but after a very bad year with deaths in the family etc my body piled on weight (12 kilos) no matter how healthily I ate and nothing I did to get back in shape would work. His book made the difference. I still workout and eat like I should but now I am finally getting te results I deserve! So happy.
Both "Turn off the hunger switch" and "Turn off the hunger switch naturally" are avail on Amazon (I just checked). - 8/7/2012 11:40:08 PM
As far as 8, or 10 lbs., in one year..not enough for me, to risk taking any kind of pill. - 8/7/2012 11:20:06 PM
Doctors have been making LOTS of money out of doing Weight Loss Surgery for $30,000 a person, or the Lap Band for $16,000 . That is a choice I wouldn't make, but lots of them do. - 8/7/2012 7:02:28 PM
It taught me a great lesson though, and now I won't do anything "temporary" for weight loss because if you can't do it for the rest of your life, the resulting weight loss will be only temporary and you'll be right back where you started except you'll have the extra baggage of additional health problems to deal with! - 8/7/2012 9:32:17 AM
According to the information provided in the article, a 300lb individual on middle-dose Qsymia can on average expect to lose just over 25lb in a year. Not impressive considering the risks. I think examining what got them to the weight and putting education and support in place is a better way to go. - 8/7/2012 5:11:56 AM
LOL - one pill makes you larger... and one pill makes you small... great line!
Seriously, phentermine (Adipex) is such a horrible drug. I have, in the past, been addicted to it, and my doctor just kept feeding it to me. Dangerous stuff...
- 8/4/2012 3:17:13 AM
The latest one I bought was also on Dr Oz reccomended list. I wish that I had read the package a little closer because I'm not so sure that I want to take it now. - 8/3/2012 10:49:53 PM
I don't see the point of the pill. Isn't a healthy diet and regular exercise going to take care of that amount of weight loss? Not to mention the potential health hazards and side effects?
- 8/2/2012 10:48:02 PM
- 8/2/2012 12:39:39 PM
- 8/2/2012 11:45:44 AM
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